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Laboratory Diagnostics of Multiple Myeloma
ČERNÝ, Jakub
The bachelor thesis on the topic Laboratory diagnostics of multiple myeloma is divided into theoretical and practical parts. In the theoretical part I introduce the hematooncological disease multiple myeloma, its laboratory diagnostics, which include biochemical, hematological, immunological, genetic and histological tests. In addition, I also present other diagnostic methods - skeletal imaging (X-ray, CT, PET/CT). I also present other pathologies that are closely related to the problem and are associated with monoclonal gammopathy. At the end of the theoretical part I briefly inform about the treatment options for this disease. For the bachelor thesis 4 objectives were set. The first aim was to summarize the laboratory testing methods currently used to diagnose MM. The second aim was to map the diagnostic procedure for the first detection of MM using a specific patient as an example. The third aim was to highlight the variability of initial findings and disease course in the form of case reports. The fourth and final aim was to use data obtained from the Institute's own department (laboratory + haematology outpatient clinic) to answer several research questions. To achieve the results of the research investigation, quantitative research methods were used by retrospective analysis of available laboratory data from LIS. Qualitative research technique of data analysis was used to write individual case reports and complete patient diagnosis. In the discussion and in the conclusion of the bachelor thesis, the results of the research questions and the evaluation of the fulfilment of the stated objectives of the thesis are summarised. Finally, the expected contribution of the bachelor thesis in current laboratory and clinical diagnosis of the disease is mentioned.
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Project ORC -cycle
Černý, Jakub ; Pospíšil, Jiří (referee) ; Fiedler, Jan (advisor)
The aim of this thesis is the project for biomass cogeneration units using ORC cycle and subsequent use of thermal energy for drying wood biomass for a briquetting line. The introducing sections describe the principle of cogeneration, organic Rankine cycle (primarily the indication of potential applications and their use in practice) and the selection of the proper working fluid. The following sections provide a technical description of the selected plants for cogeneration unit, total circulation scheme and calculation of the evaporator working fluid. The last section is devoted to the economic evaluation of three variants according to the investor's task to design a better option for implementation.
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Cogeneration Unit
Černý, Jakub ; Hrnčířová, Michaela (referee) ; Fiedler, Jan (advisor)
The aim of this thesis is a technical-economical design of cogeneration unit for drying of biomass resources for the subsequent processing. The first part of this work is devoted to biomass. There is described in detail its division into various types, their characteristics and usage, as well as the technology of drying and processing the biomass into forms of normative fuels and description of cogeneration devices that use biomass as fuel. The second section lists the input parameters from the investor for the subsequent calculation of the thermal cycle and cogeneration source selection. The last part is devoted to technical and economical evaluation of various design options and offering the better option for implementation.
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A Critical Analyse of Investing in Apartments from the Perspective of Individuals in the Czech Republic
Černý, Jakub ; Fajkus, Jiří (referee) ; Škapa, Stanislav (advisor)
The thesis deals with analysis of the residential market with a focus on housing, the current situation and in particular the issue of return on investment to purchase an apartment with his subsequent hiring. On the basis of statistical methods and economic indicators using the findings from a critical analysis of current developments will be made and estimates of rate of return of investment risk in buying and renting apartments. Economic indicators for assessing the profitability of investment are the net present value at the selected discount rate and internal rate of return.
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Detached House with Office of Tax Advisor
Černý, Jakub ; Paul, Zbyněk (referee) ; Fišarová, Zuzana (advisor)
Bachelors thesis deals with a design of a newly built detached house with office of tax advisor. The building is located in village Lhota u Lísku in Vysočina region. Detached house is designated for four family members, with one ground floor and an attic. Second building is a separated office, serving the owner of the house for his job. In its part is a garage for one personal vehicle and an attached carport for a second one. It is possible to rent the second building or rebuild it in the future. Both buildings are without cellar, roofs are both gabled with concrete roofing. Vertical constructions are designed as clay masonry, horizontal constructions as beams with clay blocks. Roof construction is wooden roof truss in the main house and wooden girders in the office building. Part of baechelors thesis is seminar paper dealing with check of selected details in terms of heat engineering.
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Property record based on RFID technology
Černý, Jakub ; Dydowicz,, Petr (referee) ; Kříž, Jiří (advisor)
This bachelor work focuses on the study of the modern technology of RFID tags and its application at Faculty of Business and Management in Brno. The main subject of this work is to use this technology as a replacement of barcode technology with the intention of raising processing speed, effectiveness and protection against stealing.
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Resort Sázava
Černý, Jakub ; Melcr, Petr (referee) ; Fišarová, Zuzana (advisor)
Subject of this diploma thesis is a design of a newly built accommodation and relaxation centre Resort Sázava. The structure is located on a sloping plot near town Sázava, in Kraj Vysočina. The locality is situated in preserved area Žďárské vrchy. The facility is divided into three buildings by their function. The buildings have rectangular shapes and have gabled roofing. The resort offers services of accomodation, boarding, conferences, relaxation and sports. The whole facility was designed in architectural study along with its functional linkups. Object SO 01 with restaurant and conference rooms was designed in detailed design documentation.
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What is the attitude of special educators to the policy of inclusion?
Jirovská, Natálie ; Mouralová, Magdalena (advisor) ; Černý, Jakub (referee)
The bachelor's thesis deals with the opinions of special educators in special schools on inclusion. Although they are not direct actors of inclusion, they are workers in education and it can be useful to know their opinion. The aim of this work is to find out the opinion of the interviewed special education teachers, and then compare them with the opinions of other respondents. In the theoretical part, I deal with the concept of inclusion, the definition of the role of a special pedagogue in a special school, I state who is a pupil with special educational needs, I present two special schools in České Budějovice, in which special pedagogues teach, who were used as respondents in the practical part, and finally, I present the theory of street- level bureaucracy and the theory of the role of line workers in public policy, with whom I continue to work in the practical part. In the practical part, I present qualitative research using four semi-structured interviews and analysis of media outputs of special educators in newspapers and on the Internet. I subsequently analyze these sources. I mainly focus on their personal opinion on inclusion, then the perception of their role in the inclusion process, trust in the system and I apply the already mentioned theories. From the results of the research, it is...
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