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National Repository of Grey Literature

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The study of hypolipidemic drug treatment on the atherogenic process in the vessel wall in experimental model of atherosclerosis I. Metelková, Marie ; Nachtigal, Petr (advisor) ; Tilšer, Ivan (referee) Cíl práce Cílem této diplomové práce bylo detekovat a kvantifikovat změny endoteliální exprese VCAM-1 a endoglinu ve stěně cévy u kmene myší C57BL/6J, kterým byla podávána aterogenní dieta. Dále byl sledován vliv krátkodobě podávaného hypolipidemika atorvastatinu na změnu v expresi těchto endoteliálních markerů. Pro vizualizaci exprese VCAM-1 a endoglinu byly využity imunohistochemické metody a ke kvantifikaci jejich exprese stereologické metody. Detailed record

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