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Scaling of arterial input function in DCE-MRI
Holeček, Tomáš ; Kolář, Radim (referee) ; Kratochvíla, Jiří (advisor)
Perfusion magnetic resonance imaging is modern diagnostic method used mainly in oncology. In this method, contrast agent is injected to the subject and then is continuously monitored the progress of its concentration in the affected area in time. Correct determination of the arterial input function (AIF) is very important for perfusion analysis. One possibility is to model AIF by multichannel blind deconvolution but the estimated AIF is necessary to be scaled. This master´s thesis is focused on description of scaling methods and their influence on perfussion parameters in dependence on used model of AIF in different tissues.
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Multichannel Image Deconvolution
Bradáč, Pavel ; Kolář, Radim (referee) ; Jiřík, Radovan (advisor)
This Master Thesis deals with image restoration using deconvolution. The terms introducing into deconvolution theory like two-dimensional signal, distortion model, noise and convolution are explained in the first part of thesis. The second part deals with deconvolution methods via utilization of the Bayes approach which is based on the probability principle. The third part is focused on the Alternating Minimization Algorithm for Multichannel Blind Deconvolution. At the end this algorithm is written in Matlab with utilization of the NAG C Library. Then comparison of different optimization methods follows (simplex, steepest descent, quasi-Newton), regularization forms (Tichonov, Total Variation) and other parameters used by this deconvolution algorithm.
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Scaling of arterial input function in DCE-MRI
Holeček, Tomáš ; Kolář, Radim (referee) ; Kratochvíla, Jiří (advisor)
Perfusion magnetic resonance imaging is modern diagnostic method used mainly in oncology. In this method, contrast agent is injected to the subject and then is continuously monitored the progress of its concentration in the affected area in time. Correct determination of the arterial input function (AIF) is very important for perfusion analysis. One possibility is to model AIF by multichannel blind deconvolution but the estimated AIF is necessary to be scaled. This master´s thesis is focused on description of scaling methods and their influence on perfussion parameters in dependence on used model of AIF in different tissues.
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|
|
Scaling of arterial input function in DCE-MRI
Holeček, Tomáš ; Kolář, Radim (referee) ; Kratochvíla, Jiří (advisor)
Perfusion magnetic resonance imaging is modern diagnostic method used mainly in oncology. In this method, contrast agent is injected to the subject and then is continuously monitored the progress of its concentration in the affected area in time. Correct determination of the arterial input function (AIF) is very important for perfusion analysis. One possibility is to model AIF by multichannel blind deconvolution but the estimated AIF is necessary to be scaled. This master´s thesis is focused on description of scaling methods and their influence on perfussion parameters in dependence on used model of AIF in different tissues.
|
|
|
Multichannel Image Deconvolution
Bradáč, Pavel ; Kolář, Radim (referee) ; Jiřík, Radovan (advisor)
This Master Thesis deals with image restoration using deconvolution. The terms introducing into deconvolution theory like two-dimensional signal, distortion model, noise and convolution are explained in the first part of thesis. The second part deals with deconvolution methods via utilization of the Bayes approach which is based on the probability principle. The third part is focused on the Alternating Minimization Algorithm for Multichannel Blind Deconvolution. At the end this algorithm is written in Matlab with utilization of the NAG C Library. Then comparison of different optimization methods follows (simplex, steepest descent, quasi-Newton), regularization forms (Tichonov, Total Variation) and other parameters used by this deconvolution algorithm.
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