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Methods of preparation and characterization of liposomal systems
Chýlková, Patricie ; Venerová, Tereza (referee) ; Jugl, Adam (advisor)
In this bachelor's thesis the properties of liposomes prepared by reference thin-film rehydration method and Mozafari method were compared. The aim of the experimental part was to determine whether the Mozafari method is convenient alternative for liposome preparation and whether thin-film rehydration and Mozafari methods produce liposomes with the same properties. The prepared liposomes were characterized in terms of size, polydispersity and zeta potential using dynamic light scattering on certain days for one month since the day of preparation. It was determined that electrostatically or sterically stabilized liposomes of identical composition prepared by either method had mutually corresponding properties.

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