National Repository of Grey Literature 37 records found  beginprevious35 - 37  jump to record: Search took 0.00 seconds. 
Preparation of encapsulated enzymes for cosmetics application
Bokrová, Jitka ; Čarnecká, Martina (referee) ; Márová, Ivana (advisor)
Presented diploma thesis is focused on testing of an appropriate form of encapsulated enzymes intended for application in cosmetic and pharmaceutical industry. For encapsulation, proteolytic enzymes bromelain, papain and collagenase were used. These enzymes were encapsulated into alginate and chitosan microparticles prepared by an encapsulator and packed into liposomes. Encapsulation effectiveness was evaluated by analysis of total proteins. Particles stability was evaluated in model and real conditions by photometrical analysis of released proteins. Proteolytic activity of released enzymes in model and real conditions were observed too. Alginate and chitosan microparticles prepared by the encapsulator were found as an appropriate form of encapsulated enzymes designed to wound healing. Encapsulation effectiveness of these particles and stability in model conditions were good in comparison with liposomes. Hydrogel and water-oil emulsion were used for analysis of particles stability at real conditions. Hydrogel was found as a good option for preservation of particles as well as proteolytic enzyme activity. Emulsion made particles less stable and proteolytic activity of enzymes decreased rapidly. Encapsulation enables long-term stabilization of biologically active compounds as well as possibility of targeted transport and controlled releasing. Presented diploma thesis suggests possibilities of application encapsulated enzymes in designing more effective formulations for wound healing.
The awareness of primary care nurses about wet healing wounds
SEDLÁKOVÁ, Dana
The method of wet healing wounds is one of the most modern way how to take care of long term cureless wounds. In the past nurses nad doctors were use to heal chronic woulds with help of dry dressings, but today we have many possibilities how to improve the quality of nursing care. The application of moist healing is highly efficient for both sides. Pacients donť have to suffer from pain for long time, re-bandages are much less hurtfull. One of the biggest advantages is that the manipulation with this modern material is so easy, that pacient is able to make re-bandage on his own. Most modern wound dressings are designed to optimize a moist wound environment and have become very good at this task. The wound fluid contains many growth factors and nutrients that assist in the proper healing of superficial wounds. Wounds that are kept moist have fewer pathogenic bacteria than overwet wounds The method of wet wound healing is helpful for pacients who suffer from chronic, open, nonhealing wounds. The work with title The Awareness of Primary Care Nurses about Wet Healing Wounds is splitted into two parts. The theoretic part of the bachelor work tries to include the complex theme of wound healing, with a view to way to advantagases of wet wound healing. Some parts of these work also discuss the awarness of primary care nurses, the cooperation between nurses and patients and the area of primary care. Results of nursing research are compiled in the experimental part of work. In the course of the research was used the quantitative method of collecting data with the technique of list of questions. The nurses which were asked to fill the questionary were from west of our country, concretely from Cheb, concretely from Cheb, Sokolov and Karlovy Vary. The research was made in offices of practicals doctors for adults and for children, on surgical units, by the dermatologist ambulances and in the home care centres. In connection with task of the bachelor work four targets were set together with five hypotheses to perminent confirmation or negation. The autoress tryed to find out if nurses who are working in primary care area have some knowledges about moist healing of wounds and if they are able to apply these knowledges in their profession. In conclusin there are the most important facts, which were ascertained and proposal on possible solution. The autoress thinks, that bachelor work could serve as an informative material for nurses and for students and at the same time could be also used as a motivation for nurses who want to provide the best care for patients at the same time.
Use of modern methods in treatment of chronic wounds
LEPIČOVÁ, Zuzana
Healing and treatment for chronic wounds are big problems and they affect overall states and fate of patients who are immobile after heavy injuries in consequence of some diseases or because of penetrating wounds. Prevention and treatment flowing from profound knowledge of anatomy, skin physiology, pathology and patho-physiology of defects origins and of healing process is currently taking a big step forward in treatment for refractory wounds. The thesis is divided into two parts. The theoretical part deals with skin anatomy and physiology, pathology and patho-physiology of origins of defects, healing processes and proper treatments of wounds, especially chronic wounds such as ``diabetic foot syndrome{\crqq}, venous and arterial ulcerations and decubital ulcers. Preventative measures against decubital ulcers are described. Documentation of refractory wounds, 3 phases of healing and continuum of healing are described in detail. Re-bandages, the local wound care, are the most significant factor of treatment. Re-bandages follow standard procedures, which involve make-ready of patients, preparations of wounds for re-bandages, preparations of instruments and make-ready of attending staff. Good re-bandage assistance is crucial. Modern treatment methods include various new types of wound cleanup (from the mechanical one, chemical one and autolysis to the enzymatic one, with the use of larva therapy, for example) as well as the usage of very effective ``moist healing{\crqq} methods. Various contact - not adhesive bandages, foams, alginates, hydro gels, antiseptic bandages, dressings with active Carbon, hydrocolloids, hydro adherent dressings, hydro fibres, bandages with active AG ions, chitosin, dressings with hyaluronic acid, collagen bandages, dressings with iodine, mupirocin, or honey. The practical part is dedicated to qualitative research, in a way of non standardised interview. There were two thesis objectives: To map the usage of modern treatments for refractory wounds and to enlighten general nurses in this field. 15 nurses, who deal with chronic wounds, from various emergency wards and hospital wards took part in the interviews. Information was collected from February 2010 to April 2010 and it was elaborated into 15 casuistries. The result of analysed answers was digested into a table. In the Discussion I analysed the particular answers and set 3 hypotheses for each domain. Domain 1: H1: Modern treatments for healing of wounds are not systematically used at most units. H2: Monolithic systems for usage and indication of modern methods do not exist at most units. H3: Statistics of chronic wounds existence is not kept at many units. Domain 2: H1: Trainings are organised by medical facilities in collaboration with distributing companies but their capacities do not satisfy the interest of applicants. H2: Most nurses declare good knowledge of chronic wound healing phases and of continuum of healing. H3: Neither managers of medical facilities nor health insurance companies have sufficient knowledge regarding the ``cost {--} benefit{\crqq} of chronic wound treatments. The Conclusion summarise the whole thesis. The importance of follow up treatment and rehabilitation for subsequent fate of afflicted patients and their families is underlined in this part.

National Repository of Grey Literature : 37 records found   beginprevious35 - 37  jump to record:
Interested in being notified about new results for this query?
Subscribe to the RSS feed.