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Determination of chlorides in pharmaceutical substances
Čutová, Michaela ; Pharm.Dr.Tomáš Schenk (referee) ; Omelková, Jiřina (advisor)
The topic of this bachelor work is a validation of the method for „Determination of chlorides in pharmaceutical substance“ is made in a form of validation of an analythical method. This titration method with potentiometric indication was developed in a company Sicor and it is used for determination of the residual chlorides volume in the substance called Pemetrexed. Validation is a process which assess suitability of a given analythic system for gaining relevant data (results). Validation constists of four tests: precision, reproducibility, lineraity and test of solution stability, although the test of reproducibility was realized in other laboratory (QC). For determnination of the chlorides was applyed titrator 716 DMS Titrino with argent combined electrode. For a data evaluation were used software tiamo 1.1 and MS Excel.
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Motivation of starting a substitute treatment by drug-addicts
KRIŠKOVÁ, Tereza
In the past yearstheformofsubstitutetreatmentfortreatmentofopiateaddiction has beenspread more and more. This thesis concentrates on thetaking-up motivationof such treatment and thethemeisdealtwithfromthe point of bio-psycho-socio-spiritual model oforigin, development and upkeepofaddiction. Thetheoretical part isdividedintofiveindividualchapters. In thefirstone, the term drugisdefined, problematicdrugtakingismentioned and a briefcharacterizationofdrugsisprovided. The second chapteraimsatopiates and opiods. Theirpracticalapplication, sorting and somaticeffects are describedhere. Opium, morfine and heroin are closelyintroduced in shortunderchapters. Thethirdchapterdealswith bio-psycho-socio-spiritual model ofaddiction, thereaders are closelyintroduced to theindividuallevelsofthis model. Then a free switch to thethemeofmotivationcomes and motivation as such ismentioned as well as otherfactorswhich play roles in thisprocesstogetherwithmotives and needsplaying a big role in motivation. Thefollowingunderchapteriscalleddrug-addiction as the source ofmotivation and craving and threefactorswhichexplainwhyaddictivematerials are, more thanotherincentives,able to evokeaddiction, are described. In the last underchaptermotivationtraining, orthechanges in motivationwith as well as withouttheprofessionalhelp, iscloselyintroduced. Thefourthchapterdealswith substitute treatment as oneoftheformsofmedical care fortheopiodaddicts. Firstly, a shortdefinitionisprovided and then in thefollowingchapterstheaims are lookedat. Theprimaryaimistheimprovementofsomatic, psychic and socioeconomicsituationof a client. Thetargetgroupisdescribed in thetermsofwhocanget such treatment and whodecidesaboutit. Thehistoryofsubstitutetreatmentismentioned, fromthefirstnoticesaboutthistreatment in the Czech Republic up to today. Thefifthchapterdescribesthepharmacologicalcomponentofthe substitute treatment. Metadon as oneofthepossibilitiesofsubstitutematerialsisintroduced to thereader as well as buprenorfin, orratherthetwopillscontaining buprenorfin, Subutex a Subuxone. Theresultsofmyresearch are presented in thepractical part. Theaimofthe thesis is to findout and describethesystemofmotiveswhichleadthedrugaddicts to determination to undergo a substitute treatment in theharmonywiththe bio-psycho-socio-spiritual model oforigin, development and upkeepofaddiction. Theresultsofthisbachelor thesis canbe a source ofinformationforsocialworkersworking in contactcentersbecauseitisherewherethework on client'smotivationusuallystarts. The thesis candefinitely serve to theprofessionalorlaical public interested in thisfield. A biggerinterestofworkwithdrugaddicts on alllevelsofthe bio-psycho-socio-spiritual model canleadfrom my work, especiallyforthetherapistsofsubstitutecenterswhoshouldwork on the spirituality oftheirclients.
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Modifications of Profit in Classical Balance Theories
Balek, Luboš ; Janhuba, Miloslav (advisor) ; Pakšiová, Renáta (referee)
The master's thesis focuses on the accounting concept of profit or loss. In the first part, the contemporary approach to the issue from both theoretical and practical point of view is described with the main focus on the determination of the distributable profit. The capital maintenance and value measurement are also dealt with for this purpose. Following the theoretical basics laid down in the previous part, the main approaches of classical balance theories are explained and their advantages and disadvantages pointed out in relation to their possible use in practice. The thesis contains illustrative examples and ends with a draft of a usable methodology based on the various concepts described in the text.
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Historical evolution view on the substance of the light
ANDERL, Jan
The principle of the seminar work is to create the skilled text which could be used such as educational material for other students to they can better understand to the evolution of opinions on the substance of the light. The work is composed from the five parts. Each part is enplaining the view of the scientists on the substance of the light from the certain period. The first part is connected to the era of the antiquity {--} the period of the first contentions about the substance of the light. The second part is intent on the era from the fifth century (Optical theory) to the nineteen century (Young theory ). The third part refers to the 20th century. The fourth part apply to the present, to the newest researches and work in the sphere of the light. The fifth part is created by the biographies of the most meaningful people who have been working on the question about the substance of the light.
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Thermophysical properties of ordinary water substance /KKE-20-2001/
Mareš, R. ; Šifner, Oldřich
The necessity of the replacement of IAPS-84 formulation with the new formulation IAPWS-IF97 is stressed in our report. Sources of the IF97 formulation, Steam Tables and software based on the new formulation are summarized. A proposal of Statement on t**computation of thermodynamic properties of ordinary (light) water substance is presented We presume that the Statement will be attached to the Report IAERA-TECDOC-949 or separately published in the data base of IAEA. News from the 2001 Annual IAPWS Me
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