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Methods of controlled propagation of fish using various hormonal preparations. A minireview
Hamáčková, J. ; Kouřil, J. ; Barth, Tomislav ; Hulová, Irena ; Barthová, J.
Common carp, grass carp, silver carp, bighead carp, African catfish, tench and European catfish are artificially stripped using hormonally induced ovulation and spermiation by GtH present in carp pituitary. Experiments proved the possibility of using GnRH analogs for induction of ovulationin other kinds (sterlet, ide, perch, pike etc.) and, in combination with dopaminergic inhibitors, also in common carp and some other kinds.
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Full biological characterization of two linear vasopressin analogues - [Phaa,D-Tyr(Et).sup.2./sup.,Aib.sup.4./sup.,Arg.sup.6./sup.,Tyr(NH.sub.2./sub.).sup.9./sup.]AVP and [Phaa,D-Tyr(Et).sup.2./sup.,Arg.sup.6./sup.,Aib.sup.7./sup.,Tyr(NH.sub.2./sub.).sup.9./sup.]AVP
Kunčarová, Pavla ; Nazarov, Elšan ; Howl, J. ; Slaninová, Jiřina
The achiral amino acid Aib was introduced into position 4 or 7 of the linear V1a-selective vasopressin antagonist [Phaa,D-Tyr(Et)2,Arg6,Tyr(NH2)9]AVP. Peptides displayed reduced affinities for both V1a and V2 receptors and high antipressor activity in vivo. Uterotonic tests in vitro revealed that these compounds also strongly interact with the oxytocin receptor (pA2=7.8 and 7.9 for Aib4 and Aib7, respectively).
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Receptor-selective enkephalin analogs
Pencheva, N. ; Barth, Tomislav
We investigated the opioid profiles of [Cys2]-enkephalin (enk) analogs and [D-Ala2,Leu5]-enkephalyl-Arg (dalargin) in in vitro bioassay system. The results showed that incorporation of hydrophilic Cys(O2NH2)2 into the enk molecule greatly increases the potency and selectivity of the analogs to ë-opioid receptors, while substitution of D-Ala2 and Arg6 into the molecule of [Leu5]-enk, to ć-opioid receptors.
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