Národní úložiště šedé literatury Nalezeno 3 záznamů.  Hledání trvalo 0.00 vteřin. 
Binding sites for oostatic peptides in organs of fly .I.Neobellieria bullata./I..
Nazarov, Elšan ; Holík, Josef ; Tykva, Richard ; Hlaváček, Jan ; Bennettová, Blanka ; Slaninová, Jiřina
Using tritiated peptides Asp-Pro, Tyr-Asp-Pro-Ala, Tyr-Asp-Pro-Ala-Pro binding experiments with homogentates on membrane preparations of ovaries were performed. Very low degree of specific binding was detected.
Detection of oxytocin binding sites in the blood vessels of chicken
Nazarov, Elšan ; Slaba, J. ; Lidická, M. ; Slaninová, Jiřina
..sup.125./sup.I-OTA was bound specifically to the membrane preparation from chicken blood vessels with B.sub.max./sub. = 128 fmol/mg of protein and .I.K./I..sub.d./sub. = 0.076 nM.
Full biological characterization of two linear vasopressin analogues - [Phaa,D-Tyr(Et).sup.2./sup.,Aib.sup.4./sup.,Arg.sup.6./sup.,Tyr(NH.sub.2./sub.).sup.9./sup.]AVP and [Phaa,D-Tyr(Et).sup.2./sup.,Arg.sup.6./sup.,Aib.sup.7./sup.,Tyr(NH.sub.2./sub.).sup.9./sup.]AVP
Kunčarová, Pavla ; Nazarov, Elšan ; Howl, J. ; Slaninová, Jiřina
The achiral amino acid Aib was introduced into position 4 or 7 of the linear V1a-selective vasopressin antagonist [Phaa,D-Tyr(Et)2,Arg6,Tyr(NH2)9]AVP. Peptides displayed reduced affinities for both V1a and V2 receptors and high antipressor activity in vivo. Uterotonic tests in vitro revealed that these compounds also strongly interact with the oxytocin receptor (pA2=7.8 and 7.9 for Aib4 and Aib7, respectively).

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