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The use of thromboelastography (TEG) in the evaluation of coagulation in patients on intensive care unit (ICU)
Durila, Miroslav ; Cvachovec, Karel (advisor) ; Stříteský, Martin (referee) ; Kovářová Kudrnová, Zuzana (referee)
Patients in the intensive care unit are in critical condition which is often accompanied by a coagulation disorder. Sepsis as a leading cause of death in critically ill patients may be associated with both hypercoagulable state with microtrombi formation in microcirculation and with increased production of endogenous heparinoids with inhibitory effects on blood clotting. Central venous catheter and arterial catheter are established in patients for hemodynamic monitoring and these are flushed with heparin to prevent their closure. Both inputs are used for blood sampling for laboratory tests such as blood count and coagulation parameters, including thromboelastography (TEG). In the first step of the work, arterio-venous differences in coagulation parameters were investigated in patients with sepsis. Higher concentration of D-dimers and lower antithrombin activity were found in venous blood. This finding can be explained by increased antithrombin consumption in hypercoagulable state and reactive hyperfibrinolysis. Inconsistency in the site of blood sampling may then lead to misinterpretation of the pathophysiological processes in the body. No significant differences were found in TEG parameters. In the second step of the work we examined how heparin commonly used for catheter flushing affects TEG-assessed...
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Optimization of the warehouse system in the selected production plant
KOVÁŘOVÁ, Zuzana
The aim of the diploma thesis was optimization of the warehouse system according to suitability for use in assortment in a selected production company focusing on material and information flows, decay processes, warehouse technology, logistic costs and relevant logistics indicators. The partial objective was to determine the critical factors in terms of management and operation in the warehouse of the selected manufacturing enterprise.
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The use of thromboelastography (TEG) in the evaluation of coagulation in patients on intensive care unit (ICU)
Durila, Miroslav ; Cvachovec, Karel (advisor) ; Stříteský, Martin (referee) ; Kovářová Kudrnová, Zuzana (referee)
Patients in the intensive care unit are in critical condition which is often accompanied by a coagulation disorder. Sepsis as a leading cause of death in critically ill patients may be associated with both hypercoagulable state with microtrombi formation in microcirculation and with increased production of endogenous heparinoids with inhibitory effects on blood clotting. Central venous catheter and arterial catheter are established in patients for hemodynamic monitoring and these are flushed with heparin to prevent their closure. Both inputs are used for blood sampling for laboratory tests such as blood count and coagulation parameters, including thromboelastography (TEG). In the first step of the work, arterio-venous differences in coagulation parameters were investigated in patients with sepsis. Higher concentration of D-dimers and lower antithrombin activity were found in venous blood. This finding can be explained by increased antithrombin consumption in hypercoagulable state and reactive hyperfibrinolysis. Inconsistency in the site of blood sampling may then lead to misinterpretation of the pathophysiological processes in the body. No significant differences were found in TEG parameters. In the second step of the work we examined how heparin commonly used for catheter flushing affects TEG-assessed...
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Development of Peruvian economy in new millenium
Kovářová, Zuzana ; Pavlík, Petr (advisor) ; Cihelková, Eva (referee)
The thesis "Development of Peruvian economy in new millenium" is divided into four chapters. The first part deals with Peruvian geography, demography nad history. The second part focuses on development of GDP and its structure, on inflation, currency, public debt and unemployment. The third part analyses the development of Peruvian trade and presents the trade with United States and European Union as a study. The final part evaluates the perspectives of economic development and on the basis of mentioned facts gives the problems that are limited for the fast growth of Peruvian economy. The result is a complete study about progress, development and limiting factors of Peruvian republic.
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Propose a system of intercontinental freight transport for commodities on specific company
KOVÁŘOVÁ, Zuzana
The aim of my bachelor thesis was to propose a system of intercontinental freight transport for chosen commodities on specific company: VOLF. To reach the aim the determination of chosen commodities selected according to the Czech statistical office and company. At the end of each part about the transports from each continent, there is comparison of the kinds of transports among themselves and then the most effective way is chosen. They are compared from time, economic and general viewpoints.
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Current stage of Chilean economy
Kovářová, Zuzana ; Pavlík, Petr (advisor) ; Machytka, Daniel (referee)
The target of my bachelor thesis is the total analysis of Chilean economy at 2010. After reading of the text anybody should be able to imagine the macroeconomic climate in Chile. The text of the work is devided in four chapters - the first one reports about the general information of territory and of Chilean history, the second one dedicates to the structure of Chilean economy and closer to the theme of mining, the third one engages in international trade with special target to bilateral relationship agreements, the fourth one is about economic challenges in the form of reconstruction after the earthquake and integration processes in Latin America.
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