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název v anglickém jazyce není uveden
Jandová, Kateřina ; Langmeier, Miloš (advisor) ; Mareš, Jan (referee) ; Hach, Petr (referee)
Hypoxia of the brain as well as the subsequent reperfusion can seriously alter the tissue microenvironment and result of the functional and structural changes of nerve and glial cells. Results of experimental studies show that some ions (e.g. Mg2+) can interfere with the brain development. To answer the question whether magnesium can modulate changes of neuronal circuits induced by hypoxia and reperfusion effect of magnesium administration on the density of nitrergic neurons (NO synthesising neurons) in the rats exposed to repeated hypoxia during the postnatal ontogeny (12, 25, and 35-day-old) was studied. NO synthesising neurons were identified according to the presence of NADPH-diaphorase (NADPH-d), the enzyme co-localized with NO synthase. Results have shown that the long-lasting intermittent hypobaric hypoxia brings about the increase of the density of NADPH-diaphorase positive neurons in all studied regions of the hippocampus in 12-day-old animals, in 25-day-old only in the hilus of the dentate gyrus, and in 35-day-old in CA1, CA3 hippocampal regions and in the ventral blade of the dentate gyrus. Contrary to that, decreased density of nitrergic neurons was found in groups of animals exposed to hypoxia till the age of 25 days in both blades of the dentate gyrus and in 35 days in the ventral blade and...
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Analysis of Decision-Making Processes in the Company
Jandová, Kateřina ; Černý, Jan (advisor) ; Tomášek, Lukáš (referee)
The bachelor thesis deals with decision-making processes in a given company. The concrete decision-making process is the product pricing. The theoretical part of this thesis describes theoretical characterization of this problem, its structure, methods of solutions and factors that operate in whole process of product pricing. A part of theoretical part is also product mix that makes the basis for that decision-making process. In analytical part is description of product portfolio of selected company. These is also chosen several concrete products that show the chosen methods of product pricing used in this company. Tha part of the thesis are author's comments on this issue.
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