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Helminth-host interactions on hormonal level
Lukesová, Hedvika ; Mikeš, Libor (advisor) ; Horák, Petr (referee)
Interactions between helminths and their hosts at the hormonal level result from their biochemical coevolution. Host hormones play an important role in the life of many helminths, and helminths are able to exploit them in some cases. For example, by expressing their own analogous hormone receptors that bind host hormones. Alternatively, by influencing the levels of host hormones, as certain hormonal environments may be (dis)advantageous for the helminths. This is the case, for example, of male mice infected with Taenia crassiceps, which undergo feminization as a result of infection. Some helminths can produce their own specific factors that influence host physiology, behaviour or appearance and may be analogs (orthologs) of host hormones. An example is the plerocercoid growth factor produced by Diphyllobothrium mansonoides, which behaves very much like a growth hormone in the host, although it differs in its primary structure. Some hormonal interactions can affect both helminth reproduction and the reproduction of their hosts. Examples of host-specific hormones that have been shown to be produced by helminths include, e.g., the ecdysteroid hormones - ecdysone and ecdysterone. A full understanding of the hormonal interactions between helminths and their hosts may lead us to find new treatments for...
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Mesocestoides spp. - the spectrum of species, hosts, and life cycle modes
Zavadil, Ondřej ; Horák, Petr (advisor) ; Skála, Vladimír (referee)
Tapeworms of the genus Mesocestoides, which belong to the order Cyclophyllidea, are parasites of carnivorous vertebrates. Their larvalstages of tetrathyridiaare found in a wide range of tetrapod intermediate hosts. Within the genus, there is an anomalous species Mesocestoides corti, whose tetrathyridia reproduce in hosts by asexual longitudinal division. There is no mention of the possibility of such reproduction in other species. Thus, the laboratory strain of M. corti is widely used as a model organism that is well maintained under in vivo and in vitro conditions due to its asexual reproduction. Four other species are known to occur in the genus and are described by both morphological and molecular data. The remaining known species are named only on the basis of morphology. Adults are characterised by their rare morphology. This includes the ventromedian position of the genital atrium, the paired vitelline glands, and in gravid proglotids, developed paruterine organ, which contains eggs with oncospheres. The life cycle has not been yet explained, but it is assumed that the putative cycle involves three hosts. An alternative hypothesis considers the possibility of a two-host life cycle.
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Heating system of the apartment building
Rosíková, Barbora ; Horák, Petr (referee) ; Vyhlídalová, Karolína (advisor)
The aim of this bachelor thesis is to design a heating system for an apartment building. The thesis is divided into theoretical, computational and design parts. The theoretical part deals with the regulation of the heating system. The computational part deals with the actual design and method of heating the apartment building and hot water preparation. Three low-temperature gas boilers are chosen as the heat source and the source for hot water heating, which are connected in a cascade manner. The flats are connected to manifolds and headers located on each floor of the building in the corridor. Plate, designer and tubular heating elements are proposed in the building. The project section contains the graphic design of the project, i.e. the project documentation and finally the technical report is placed at the end.
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Energy-saving family house in Zborovice
Kovář, Vilém ; Horák, Petr (referee) ; Počinková, Marcela (advisor)
The aim of my bachelor’s thesis is to design a detached energy efficient house for a four member family. The building is located in Zborovice village in a housing area that is yet to be constructed. It is a two-story building with a rectangular shaped floor plan and a flat roof. On the first floor is a living room connected with a kitchen, a bathroom, a toilet and a utility room. There is a balcony door in the living room that leads to a terrace on a garden. On the second floor there is a master bedroom with a walk-in closet, two rooms for children, an office, a bathroom and a toilet. Structural system of the building is masonry system designed from sand-lime blocks. Horizontal load-bearing structures and foundations are designed from cast-in-place reinforced concrete. The building is supplied with potable water from a water main and with electricity from an electric distribution system. Some electric energy will be produced by photovoltaic panels. Waste water will be discharged into a sanitary sewer. Rainwater will be collected into a harvesting tank and used for irrigation. Ventilation in the building is provided by a MVHR system. Heating system is designed as an underfloor heating powered by an air to water heat pump. On the Energy performance certificate is the building rated as A.
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Design of a heating system for a multifunctional house
Barták, Jiří ; Horák, Petr (referee) ; Vyhlídalová, Karolína (advisor)
The bachelor thesis is divided into the theoretical, computational and project part. In the theoretical part, I deal with the design and description of the ground - water heat pump for the object. In the computational part, I deal with the design of the heating system and a hot water preparation in the building of the multifunctional house Rezidence Chelčická in České Budějovice. The building has four floors. On the first floor there is a commercial premises with garages and on the remaining floors there are residential units. The building is designed with a water-ground heat pump, indirect heating tank for hot water preparation and heating of the building is provided by floor convectors, plate and pipe units. The last part of the project includes a technical report and drawings for the specified object.
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Heating and preparing of domestic hot water via solar system
Lustigová, Andrea ; Adam, Pavel (referee) ; Horák, Petr (advisor)
The aim this bachelor thesis is the design of heating and preparing of domestic hot water via solar system. The theoretical part deals with the solar systems, solar collectors and stagnation of solar systems. The second part deals with a separate proposal heating and preparing of domestic hot water in a family house. As a heat source was proposed condensing boiler and solar collectors. The hot water is also ensured condesing boiler and solar collectors. The third part consist of a technical report and drawings heating of the specified object.
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Application of renewable energy sources in civil construction
Sedlák, Tomáš ; Počinková, Marcela (referee) ; Horák, Petr (advisor)
The aim of this Diploma thesis is the design of solar collectors. The thesis is consists from three parts. The first part describes the technical design of solar collectors and solar systems. The second part contains with design size of the collector area for the two selected variants. The third part addresses the experimental measurements located on the real building. The output of third part is the economic evaluation of the solar system.
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Heating and cooling systems in office operations
Dostál, Petr ; Horák, Petr (referee) ; Formánek, Marian (advisor)
The diploma thesis deals with the design of the heating and cooling system, inclu-ding hot water preparation for the administrative part of the production hall. The first part of the thesis briefly discusses the history of heating and cooling of office buildings, legislative requirements and current solutions. The second part contains the design of the entire heating and cooling system with heat pump as a source of heat and cold. The final part of the thesis describes the experimental measure-ment and evaluation of the efficiency of the ice rink source.
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Heating multifunctional building
Čajčíková, Jolana ; Horák, Petr (referee) ; Počinková, Marcela (advisor)
The theme of this bachelor´s thesis are problems of condensing gas boiler rooms in the theoretical part and heating multifunctional building in the calculation part. The four-floor multifunctional building is situated in Brno in a slightly built-up area and includes commercial units, classrooms and administrative units for rent, an IT company and a restaurant for 120 people situated in the fourth floor. The heat source for this building is a gas condensing boiler room. The heating surface consists of steel panel radiators. There is forced ventilation installed in the building.
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