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Warm-air heating and ventilating system for low-energy family house
Musil, Zdeněk ; Katolický, Jaroslav (referee) ; Jaroš, Michal (advisor)
The diploma thesis deals with warm-air heating and ventilation system of energyefficient family house. The part of thesis is theoretical introduction to low-energy and passive houses, ventilation and heating. The proposal itself is based on the applicable standards and includes all progressive steps, including the calculation of the thermal performance and sizing individual parts of the system. The drawing project documentation is listed in appendixes.
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Forming Technology of Thin Sheets
Musil, Zbyněk ; Žák, Ladislav (referee) ; Dvořák, Milan (advisor)
This bachelor‘s thesis deals with technology of mechanical working of the sheetmetals by cutting for rotary and non-rotary single parts. The first part deal with common dissertation about surface mechanical working, mainly about cutting and meaning of cutting gap in accordance with final cutting. The second part deals with transfer of the new pieces of knowledge from foreign technical literature of surface mechanical working. In the last part there is done an aplication on the particular component.
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Application ISA 95 standard to the automation barman machine
Musil, Zdeněk ; Knobloch, Tomáš (referee) ; Štohl, Radek (advisor)
This diploma thesis deals with the design and application of the ISA 95 standard for a semi-automatic barman machine. The thesis is divided into theoretical and practical part. The theoretical part deals with the description of the ISA 95 models, together with FactoryTalk platform and its products related to the ISA 95 standard. In the practical part batch procedure is designed and applied on the machine. Based on this, implementation of standard ISA 95 using Rockwell Automation products is made. The last chapter of this thesis deals with verification of functionality and overall system design, from which concludes an overall machine performance and production deficiencies.
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Heating and ventilating of low-energy and passive houses
Jankola, Mario ; Musil, Zdeněk (referee) ; Jaroš, Michal (advisor)
The Bachelor's thesis focuses on heating and ventilation of low-energy and passive houses. The beginning chapters describe and explain basic principles of these buildings and basics of air-handling systems. The main part of the work overviews contemporary heating and ventilation systems while pointing out their advantages and disadvantages. The last chapter consists of realistic blueprint for low-energy family house, including specifications on heating and ventilation systems, as well as evaluation of their efficiency.
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Microbiological hazards in HVAC systems
Musil, Zdeněk ; Charvát, Pavel (referee) ; Kolbábek, Antonín (advisor)
This bachelor thesis deals with microbiological hazards in HVAC systems, especially in air condition systems. There is noted the basic information from related fields. The same microbiological hazards are divided in health risk and in microbiological corrosion. In the last part of this thesis are mentioned possibilities of their elimination and recommendation for prefiguring of them.
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Implementation of the air-ground heat exchangers in condition of the Czech Republic
Macenauerová, Tereza ; Musil, Zdeněk (referee) ; Kolbábek, Antonín (advisor)
This work presents the implementation of ground heat exchangers for air-conditioning systems of buildings in the Czech Republic, especially in south Moravia. The purpose is to find basic information about specific devices - such as the type of heat exchanger, material of pipeline, the method of suction (filtration), outlet of condensate, etc. These are parameters that investor can decide before the realization. Exercise equipment is dependent on the parameters that investor can not decide (eg. type of soil, disposition of land, surrounding climate). The work is based on a questionnaire study (part of junior project FSI-J-12-24) form 2012 which was solved with concrete owners of realized devices. A part of the ground heat exchangers comes from the implementation of energy-efficient houses KARON s.r.o. company, the basic parameters of the these exchangers are provided by its managing director Ing. Stanislav Karasek. Other devices have been traced in the database of passive houses in the Czech Republic - managed by the Passive House in Brno. The work summarizes some of knowledge of owners, shows the most often used types and values the importance of proper design of the whole device.
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Multiple sclerosis: correlation of gene expression and response to immunomodulatory therapy
Kleinová, Pavlína ; Kubala Havrdová, Eva (advisor) ; Taláb, Radomír (referee) ; Musil, Zdeněk (referee)
KLEINOVÁ, Pavlína. Roztroušená skleróza mozkomíšní: korelace genové exprese a odpovědi na imunomodulační léčbu [Multiple sclerosis: correlation of gene expression and response to immunomodulatory therapy]. Praha, 2023. 107 s., 3 přílohy. Disertační práce. 1. lékařská fakulta Univerzity Karlovy v Praze. Vedoucí práce Eva Kubala Havrdová. Abstract Multiple sclerosis is a chronic autoimmune disease of the central nervous system with a genetic component, modifiable with immunomodulatory therapy. It is assumed that genetic factors influence the course of the disease and the therapeutic response. The thesis presents the results of two studies investigating the genetic background of multiple sclerosis. In the first study, the influence of the (GT)n polymorphism of the promoter of the HMOX1 gene for heme oxygenase 1 affecting its expression was investigated in people with multiple sclerosis. No effect of this polymorphism on the course of the disease was observed. We confirmed the effect of immunomodulatory therapy on delaying disease progression. The second study, called the Genotype/Phenotype Project, is a multicentre international genome-wide association study aimed at detecting single nucleotide polymorphisms associated with severity of multiple sclerosis. It has been shown that common genetic variants with...
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Synthesis and the structure-activity relationship study of photosensitizers from azaphtalocyanines group
Musil, Zbyněk ; Doležal, Martin (advisor) ; Hartl, Jiří (referee) ; Lang, Kamil (referee)
We have prepared a number of variously substituted precursors based on pyrazine-2,3- dicarbonitrile, phthalonitrile and quinoxaline-2,3-dicarbonitrile. These substances formed macrocycles and each of them was separated (if possible), purified and sufficiently characterized. In this way were prepared several series of products which were used to elucidate the influence of structural changes on physical and photodynamical properties. We found out that the zinc complexes of azaphthalocyanines which were substituted with bulky groups binding to the macrocycle core via heteroatom of sulphur were the best from the point of view of photodynamical properties. These substances were characterized by high production of singlet oxygen, sufficient photostability, maximum absorption at longer wavelenght and poor aggregation which provides a high-quality incorporation into unilamelar liposomes. Based on aforementioned results we prepared photosensitisers containing one funtional group which could be possibly used as the third generation photosensitisers. By the incorporation of four benzene cores into tetrapyrazinoporphyrazine macrocycle was the absorption maximum shifted to the range of app. 750 nm which is cinsidered as optimal from the point of view of photodynamical effect in living tissues.
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Typology of the EU asylum policy in relation to asylum seekers
Musil, Zbyněk ; Janská, Eva (advisor) ; Šánová, Lucie (referee)
The aim of the thesis is an outline of the evolution of European asylum policy of asylum policies towards asylum seekers within seven EU member countries since 1990. The brief description of common trends in asylum policy in European Union and EFTA (European Free Trade Zone) member countries and outline of current policy towards asylum seekers, where current living conditions are part of it. Also the position of asylum seekers in specific spheres such as education, right to work, financial and social security, health service and accommodation is discussed. Another goal is to compare the practices in the asylum policy in the Czech Republic with the policies towards the asylum seekers of other six EU member countries - Denmark, France, Germany, Republic of Ireland, the Netherlands and the United Kingdom. There is also an introduction of governmental steps which deal with the immigration law or asylum law and therefore regulate the living conditions of asylum seekers in their country.
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