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Hippocampal coding of positions of inaccessible objects
Hrůzová, Karolína ; Stuchlík, Aleš (advisor) ; Kudláček, Jan (referee)
The survival of the animals depends on their ability to memorize locations and to use behavioral spatial navigation strategies. The crucial structure for this type of behavior and memory is the hippocampus, by its ability to create a cognitive map. In this structure, there are specialized pyramidal cell called place cells. They respond by their complex firing pattern to specific animal's location in the environment. Even though many studies have investigated the role of hippocampal pyramidal cells in spatial navigation and object position discrimination, their function during inaccessible object position discrimination is not yet clarified. In our experiment, rats were trained in a behavioral task to discriminate between rewarded and nor- rewarded positions of object located in an inaccessible space. We investigated the role of individual hippocampal cells during this task by single neuron electrophysiology. The first aim of this study was to decide which of two configurations of objects presented on a computer screen during spatial object discrimination task rats can discriminate easily. The second aim is to show whether and how information about the position of inaccessible objects is represented in the hippocampus using single-neuron electrophysiology. We found out, that animals did not reach...
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Hippocampal coding of positions of inaccessible objects
Hrůzová, Karolína ; Stuchlík, Aleš (advisor) ; Kudláček, Jan (referee)
The survival of the animals depends on their ability to memorize locations and to use behavioral spatial navigation strategies. The crucial structure for this type of behavior and memory is the hippocampus, by its ability to create a cognitive map. In this structure, there are specialized pyramidal cell called place cells. They respond by their complex firing pattern to specific animal's location in the environment. Even though many studies have investigated the role of hippocampal pyramidal cells in spatial navigation and object position discrimination, their function during inaccessible object position discrimination is not yet clarified. In our experiment, rats were trained in a behavioral task to discriminate between rewarded and nor- rewarded positions of object located in an inaccessible space. We investigated the role of individual hippocampal cells during this task by single neuron electrophysiology. The first aim of this study was to decide which of two configurations of objects presented on a computer screen during spatial object discrimination task rats can discriminate easily. The second aim is to show whether and how information about the position of inaccessible objects is represented in the hippocampus using single-neuron electrophysiology. We found out, that animals did not reach...
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Techniques of intracranial EEG processing in a model of temporal lobe epilepsy
Kudláček, Jan ; Jiruška, Přemysl
To understand the role of various limbic structures in pathophysiology of temporal role epilepsy requires understanding of its functional organization. We have developed technique of recording of spontaneous and evoked acitvity in chronic model of temporal lobe epilepsy. In addition, we created a computer programme which allows sequential processing of large data sets and analysis and quantification of spontaneous epileptic activity and evoked potentials. This programme implements various techniques of seizure, HFO and interictal discharge detection
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The Analysis of Hungarian Indebtedness after 1989
Kudláček, Jan ; Petrášek, František (advisor) ; Vokoun, Marek (referee)
Hungary has struggled with budget problems throughout its post-socialist history. With knowledge of economic theory it is possible to analyze the evolution of Hungary's debt after 1989 and thus deduce its weaknesses. Populism and fiscal irresponsibility have characterized majority of Hungarian governments to some extent. Hence, the key to understanding the debt of Hungary may be found on the political level of budgetary policy. With regard to the economic situation, Hungary was forced to implement significant cost-saving measures in recent years. These measures are evaluated at the end of the work. They can be crucial not only in terms of the budgetary situation but also with respect to the perspective on the future economic development and competitiveness of the entire economy.
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The Evolution of Hungarian Debt
Kudláček, Jan ; Antoš, Ondřej (advisor) ; Vebrová, Ludmila (referee)
In the world of rising public sectors, investigation of government deficits and increasing government debts is starting to be important both in theoretical economics and political reality. Hungary is one of the EU member countries with the major public debt problems. As primal cause of Hungarian debts, the trauma of revolutionary year 1956 could be accepted. Government officials began "to bribe" Hungarian citizens by many social security benefits and government expenditures which were so large that government revenues couldn't have covered them. This course led to culminating government debt in relation to ignorance of economic reality. There weren't considerable changes in this evolution even after 1989. Government debt is still the biggest macroeconomic weakness of Hungary, which financial crisis has revealed.
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