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National Repository of Grey Literature 3 records found  Search took 0.01 seconds. 
Neuroactive steroids and addictions
 Jandíková, Hana ; Vondra, Karel (advisor) ; Miovský, Michal (referee) ; Kršek, Michal (referee)
Neuroactive steroids are a group of steroid hormones which act non-genomically to influence the neuron excitability of neuronal synapses. Addictive substances can interfere with the synthesis of neuroactive steroids through many mechanisms, affecting their levels and changing their functionality. At the same time, neuroactive steroids play a role in the development of addiction, since their levels change during attempts to quit and therefore affect the success of treatments for addiction. This study focuses on the relationships between individual addictive substances and neuroactive steroids, the individual functional mechanisms and how they influence each other. It is generally known that addictive substances result in the release of anxiolytics that act on neuroactive steroids. This plays a role in the development of addiction. We also describe in detail the effect of smoking on steroid hormones and the endocrine system in general. Using tobacco addition as a model, we studied the relationship between addiction and neuroactive steroids. As part of my doctoral studies we performed a prospective study that followed changes in the steroid spectra induced by smoking as well as when quitting smoking. We also developed a predictive model to predict the likelihood of success in treating tobacco...
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Proper names in Czech literature about Saint James´ Way.
 OROPEZA PEŇA JANDÍKOVÁ, Hana
This thesis deals with the phenomenon of proper names in a specific area of written Czech literature about the Spanish pilgrimage route called Saint James´ Way (Svatojakubská cesta in Czech). The theoretical part first describes definition, different types of classification and correct orthography of proper names in Czech and Spanish. Then it deals with the Galician language as the cooficial language of the Galician autonomous Spanish region where the pilgrimage route ends. The Galician toponymy and basic rules of national Spanish press related to the use of cooficial languages such as Catalan, Galician and Basque in comparison to Spanish are also covered. The last chapter focuses on general problems associated with the translation of proper names into other foreign languages. The main task of the practical part of this thesis is to analyse two specific books written in different genres. Some problems connected to this process are explained in the beginning, and afterwards they are evaluated and contrasted with the results of various classifications that had been made within the proper names in both publications. One chapter is dedicated to Galician proper names and finally comes the discussion of the correctness of orthography employed by the authors. The conclusion sums up the result of the whole analysis.
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Route of Santiago de Compostela as a Religious Pilgrimage. Possibilities of the Use of Religious Tourism for the Increase of Tourist Trade. THE PAST AND THE PRESENT OF THE ROUTE OF SANTIAGO DE COMPOSTELA or FROM THE TRADITIONAL CHRISTIAN PILGRIMAGE TO AN ALTERANTIVE TOURIST TRACK.
 OROPEZA PEŇA JANDÍKOVÁ, Hana
This bachelor thesis describes evolution and changes concerning Spanish pilgrimage way called Saint James´ Way (Svatojakubská cesta in Czech). The main topic is a recent increasing link between this route and tourism, reasons and consequences of this trend and its background. The first chapters introduce the history of St. James´ Way, its symbols and the main routes. The next step is the analysis of different perception of this pilgrimage way nowadays and in the past and the mention of some interesting statistical figures concerning modern pilgrims. Other part talks about the influence of St. James´ Way over economy and tourist trade in Galician region, the system of its support and promotion and the results of a public inquiry evaluating the success of the advertising campaign in abroad. The last chapter is dedicated to the relations between St. James´ Way and Czech Republic.
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