National Repository of Grey Literature 26 records found  beginprevious15 - 24next  jump to record: Search took 0.01 seconds. 
Vnímavost k navození nazální a orální tolerance je nezávislá na přítomnosti mikroflóry
Repa, A. ; Kozáková, Hana ; Hudcovic, Tomáš ; Štěpánková, Renata ; Hrnčíř, Tomáš ; Tlaskalová, Helena ; Pollak, A. ; Wiedermann, U.
The development of mucosal tolerance to major allergic component of birch pollen in relationship with presence of intestinal microflora was the aim of presented study. Germ-free (GF) or conventionally reared (CV) BALB/c mice were intragastrically or intranasally pre-treated with Bet v 1 prior to sensitization performed by subcutaneous injections of Bet v 1. Oral as well as intranasal tolerance induction led to a significant reduction of allergen-specific antibody levels and IgE basophil degranulation, as well as cytokine production in vitro in both GF and CV mice. The importance of the microflora for mucosal tolerance induction in GF mice remains therefore a matter of debate
Vliv střevních bakterií na vývoj kolitidy u SCID myší po přenosu CD4+CD45RB high T buněk a na změny těsných spojů (TJs) a Panetových buněk
Štěpánková, Renata ; Powrie, F. ; Kofroňová, Olga ; Kozáková, Hana ; Hudcovic, Tomáš ; Hrnčíř, Tomáš ; Tlaskalová, Helena
In the model of colitis developing in T cell reconstituted SCID mice pronounced morphological impairment of colon, was accompanied by structural changes of tight junctions and decreased expression of alpha defensins in terminal ileum
Vliv střevní mikroflóry na endotoxinový šok
Hrnčíř, Tomáš ; Kobayashi, K. ; Flawell, R. A. ; Hudcovic, Tomáš ; Kozáková, Hana ; Štěpánková, Renata ; Tlaskalová, Helena
Endotoxin shock is the most severe complication of sepsis. Lipopolysaccharide (LPS) or endotoxin, a structural component of gram negative bacteria, is a major effector and can activate the innate immune system and lead to multiple organ failure, termed endotoxin shock. In our project we study the effect of intestinal microflora on the susceptibility to endotoxin using a model of germ-free and specific pathogen free mice
Slizniční imunita, střevní mikroflora a nespecifické střevní záněty
Tlaskalová, Helena ; Štěpánková, Renata ; Sokol, Dan ; Rossmann, Pavel ; Cukrowska, Božena ; Hudcovic, Tomáš ; Tučková, Ludmila ; Kozáková, Hana ; Řeháková, Zuzana ; Hrnčíř, Tomáš ; Drastich, Pavel ; Frolová, Lenka ; Powrie, F. ; Uhlig, H. ; Bland, P. W.
Etiological role of intestinal microflora and abberant function of mucosal immunity in development of inflammatory bowel disease is discussed. Animal models of human IBD are described and characterized
Influence of microflora in development of intestinal inflammation induced by dextran sodium sulfate in mice
Hudcovic, Tomáš ; Štěpánková, Renata ; Cebra, J. ; Tlaskalová, Helena
To elucidate the participation of intestinal microflora and the role of E.coli in the development of the acute and the chronic.
Protective effect of epidermal growth factor (EGF) in experimentally induced enertopathy in non-suckling baby rats
Štěpánková, Renata ; Kofroňová, O. ; Kozáková, Hana ; Hudcovic, Tomáš ; Tlaskalová, Helena
Our work aimed a study of morphological changes in the small intestine, especially in the jejunum, of unsuckled artificially reared young rats which received gliadin in neonatal period compared with pups which received artificial milk diet supplemented with EGF.
Influence of microflora in development of intestinal inflammation induced by dextran sodium suofate in immunocompetent (BALB/c) and immunodeficient (SCID) mice
Hudcovic, Tomáš ; Štěpánková, Renata ; Cebra, J. ; Tlaskalová, Helena
This studyaimed at setablishing the significance of intestinal microflora and role of E. coli in tedevelopmint of the acute and the chronic phase of the experimentally induced ulcerative colitis.

National Repository of Grey Literature : 26 records found   beginprevious15 - 24next  jump to record:
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1 Hudcovic, Timoteus Jan
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