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Stress-strain analysis of anastomosis between artery and artificial vascular graft
Hrubanová, Anna ; Švancara, Pavel (referee) ; Burša, Jiří (advisor)
This bachelor’s thesis deals with anatomy and pathology of arteries and possibilities of their replacement with vascular grafts. The first part of the thesis describes structure and mechanical properties of arterial wall. Furthemore, the biological and mechanical properties of vascular grafts and their influence of healing process are described. The second part of this thesis starts with non-linear calculation of deformation of arterial wall using generalized Hooke’s law. The analytical calculation of connection of artery and vascular graft using cylindrical momentum shell theory was made at the end of this thesis. Description of limitations of this method is also included.
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Impact of material properties of tissues on stresses in a pathological carotid artery
Hrubanová, Anna ; Návrat, Tomáš (referee) ; Burša, Jiří (advisor)
This thesis deals with determination of representative constitutive model for describing atherosclerotic carotid artery behavior. The first part of the thesis provides brief summary of medical knowledge needed as well as detailed describtion of current experimental methods for determination of mechanical properties of atherosclerotic arteries. The main part is focused on mechanical testing of atheroslecotic carotid arteries. The description of sample preparation, testing device and the experiment itself is involved. Statistical analysis of measured data is done, focusing on comparison of factors potentially influencing mechanical behavior. In conclusion, the FEA analysis on simplified geometry of carotid artery with atheroma is performed. Emphasis is placed on the impact of material model obtained from experiments on equivalent stress in fibrous cap.
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The impact of freezing of arterial tissue on its stress-strain response
Horák, František ; Hájek, Petr (referee) ; Hrubanová, Anna (advisor)
This bachelor thesis deals with freezing of the arterial tissue at -20 °C and its impact on mechanical properties of artery. The introductory part focuses on basic medical terms related to the issue followed by presentation of scientific publications dealing with artery tissue freezing. The attention is mainly paid to measurements and evaluation of results. The main part of the thesis contains description of the methodology of biaxial tensile test of porcine artery tissue with process of measuring the artery’s Young's modulus. Statistical analysis is used to determine the impact of freezing on mechanical properties of the artery. Description of limitations of this experiment is also included.
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Computational modeling of arterial stents
Ondříšková, Tereza ; Hrubanová, Anna (referee) ; Fischer, Jiří (advisor)
This thesis deals with computational modeling of self-expandable and balloon-expandable arterial stents. The introductory part of the thesis is devoted to a brief overview of basic medical knowledge related to the circulatory system and cardiovascular diseases. Then, a review of constitutive models of soft tissues and arterial stents is processed, including their historical development, classification, and materials used for their production. An experimental tensile test of a nitinol wire is also included, based on which a constitutive model describing the behavior of shape memory alloys is selected. The main part is focused on the computational modeling of the interaction between an artery affected by an atherosclerotic plaque with a nitinol self-expanding stent and with a steel balloon-expandable stent. An analysis of radial displacements on the artery model wall and resulting stress states is carried out. Finally, these two approaches are compared in terms of the enlargement of the cross-sectional area of the given artery.
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Impact of material properties of tissues on stresses in a pathological carotid artery
Hrubanová, Anna ; Návrat, Tomáš (referee) ; Burša, Jiří (advisor)
This thesis deals with determination of representative constitutive model for describing atherosclerotic carotid artery behavior. The first part of the thesis provides brief summary of medical knowledge needed as well as detailed describtion of current experimental methods for determination of mechanical properties of atherosclerotic arteries. The main part is focused on mechanical testing of atheroslecotic carotid arteries. The description of sample preparation, testing device and the experiment itself is involved. Statistical analysis of measured data is done, focusing on comparison of factors potentially influencing mechanical behavior. In conclusion, the FEA analysis on simplified geometry of carotid artery with atheroma is performed. Emphasis is placed on the impact of material model obtained from experiments on equivalent stress in fibrous cap.
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Comics adaptations in literatury education at elementary school and high school
Hrubanová, Anna ; Klumparová, Štěpánka (advisor) ; Komberec, Filip (referee)
This thesis deals with the use of comic adaptations in literary lessons at primary and secondary schools. The aim of this work is to map available comic adaptations of literary works written by Czech authors. The comic adaptations of Franz Kafka's novella The Metamorphosis will be evaluated based on pre-selected criteria. Part of the work will also be a comparison of the original text with the selected comic adaptation and noting the changes in the fictional world created by transferring it to the comic medium. The work will help teachers to understand the theory of comics. Theoretical knowledge will be applied in the creation of two teaching blocks built for the purposes of literary education at primary and secondary schools. The concrete implementation of both teaching blocks in practice will be compared.
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Stress-strain analysis of anastomosis between artery and artificial vascular graft
Hrubanová, Anna ; Švancara, Pavel (referee) ; Burša, Jiří (advisor)
This bachelor’s thesis deals with anatomy and pathology of arteries and possibilities of their replacement with vascular grafts. The first part of the thesis describes structure and mechanical properties of arterial wall. Furthemore, the biological and mechanical properties of vascular grafts and their influence of healing process are described. The second part of this thesis starts with non-linear calculation of deformation of arterial wall using generalized Hooke’s law. The analytical calculation of connection of artery and vascular graft using cylindrical momentum shell theory was made at the end of this thesis. Description of limitations of this method is also included.
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