National Repository of Grey Literature 17 records found  1 - 10next  jump to record: Search took 0.01 seconds. 
Determination of n-octanol/water partition coefficient (Kow) of perfluorinated acids
Skrottová, Anežka ; Rucki, Marian (advisor) ; Tichý, Miloň (referee)
Perfluorinated compounds are organic compounds in which all hydrogen atoms in a carbon chain are substituted with fluorine atoms. These compounds are highly stable, persistent and bioaccumulative. They are purely anthropogenic compounds contained in biota and abiota. Partition coefficient between n-octanol and water is the essential toxicological parameter of a compound. This parameter helps us to assess behaviour of compound in the environment as well as in the living organisms. The shake flask method and the RP-HPLC method were employed to measure the Kow of nine perfluorinated acids. Using the shake flask method, the surface activity of compounds and the acid dissociation caused false results of the measurement. But behaviour of these compounds in the environment can be assess. Accurate and precise results were measured by the RP-HPLC method using an acetate buffer. Log Kow of perfluoro- carboxylic acids, with the carbon chain length of 5-14, were found out, their final value ranging between 1.66 and 5.10. Log Kow of acid with 12 carbons was estimated based on the linear regression of dependence of log Kow on the number of carbons. There were significant differences in the results obtained by various software. Thus, the results cannot be considered relevant. These software are not suitable for...
Alternativní metoda pro stanovení akutní toxicity chemických látek a odhad akutní toxicity jejich směsí
Státní zdravotní ústav, Praha ; Výzkumný ústav organických syntéz, Centrum ekologie, toxikologie a analytiky, Pardubice-Rybitví ; Tichý, Miloň
Úkolem projektu bylo zjistit, zda údaje o akutní toxicitě, měřené v testech na obratlovcích, lze odhadnout výpočtem z údajů o akutní toxicitě, získaných na nižších organismech, případně z fyzikálně-chemických vlastností chemikálií.

National Repository of Grey Literature : 17 records found   1 - 10next  jump to record:
See also: similar author names
3 TICHÝ, Martin
1 Tichý, M.
1 Tichý, Marek
1 Tichý, Marko
3 Tichý, Martin
14 Tichý, Michal
2 Tichý, Mikuláš
6 Tichý, Milan
1 Tichý, Miloslav
3 Tichý, Miloš
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