National Repository of Grey Literature 3 records found  Search took 0.00 seconds. 
Characterization of eukaryotic translation initiation factor 3 subunits (eIF3) in A. thaliana male gametophyte
Linhart, Filip ; Hafidh, Said (advisor) ; Retzer, Katarzyna (referee)
From RNA-to-protein, translation initiation and protein synthesis is mediated by trans-acting factors that recognize mRNA features common to almost all eukaryotes. Eukaryotic translation initiation factor 3 complex (eIF3) is a highly conserved protein complex that recognizes 5'-CAP elements of the mRNA to initiate translation. eIF3 consists of nine subunits, three of them having two isoforms: eIF3A, eIF2B1, eIF3B2, eIF3C1, eIF3C2, eIF3D, eIF3E, eIF3F, eIF3G1, eIF3G2, eIF3H and eIF3K. This work deals with functional characterization, expression and subcellular localization of eIF3B1, eIF3B2 and eIF3E in Arabidopsis thaliana male gametophyte and interaction of eIF3E with the Constitutive photomorphogenesis 9 (COP9) complex as a regulatory complex of eIF3E post-translational control. Here we show that depletion of eif3b1 or eif3b2 is not gametophytic lethal and that the two protein might function redundantly, whereas, knockout of eIF3E causes male gametophyte lethality. Interestingly, eif3b1 show post-fertilization defects during embryogenesis, suggesting that its redundancy with eIF3B2 is restricted to the gametophyte. Gene expression studies revealed high expression of eIF3 subunits in actively dividing zones of leaf primordia, root meristem and root elongation zones as well as in the vegetative...
The development and current position of BRICS within the international trade, politics and investment relations
Linhart, Filip ; De Castro, Tereza (advisor) ; Sejkora, Jiří (referee)
Brazil, Russia, India, China and South Africa (BRICS) are identified as key countries on the development of the world economy. The post-crisis economic situation evolves in those countries favorably than in the current world centers. The question remains, however, the long-term sustainability of this growth, which is subject to joint cooperation by countries in addressing political, trade and investment issues. The thesis, therefore, addresses the common features in these areas leading to a coherent cooperation in solving their current development and future positioning in the world economy. The thesis is structured in three chapters of the above-mentioned areas, which give us an objective view of the current position of BRICS and define common characteristics and interests of a unified collaboration to sustain their development.

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