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Factors influencing the metabolism of homocysteine in selected diseases with complex etiopathogenesis
Veselá, Kamila ; Anděl, Michal (advisor) ; Nečas, Emanuel (referee) ; Rušavý, Zdeněk (referee) ; Poledne, Rudolf (referee)
At present, the great medicine to develop molecular genetic techniques, which significantly help to explain the causes of illnesses. In some diseases the genetic basis is well known. These are primarily contingent on monogenic diseases. Unfortunately, many diseases remain the genetic cause is still unknown. The largest group is the so-called complex diseases, where the origin and development of disease involving both genetic and nongenetic factors. These diseases include atherosclerosis, diabetes mellitus, orofacial clefts, preeclampsia, neural tube defects, and many others. Complex diseases are serious health and social problem in developed countries. Clasification of risk factors is the subject of much attention, because knowledge of these factors offer opportunities for effective prevention and treatment. The aim of my work was to obtain new knowledge of factors affecting homocysteine metabolism with regard to the formation of some complex diseases in the Czech population.
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Factors influencing the metabolism of homocysteine in selected diseases with complex etiopathogenesis
Veselá, Kamila ; Anděl, Michal (advisor) ; Nečas, Emanuel (referee) ; Rušavý, Zdeněk (referee) ; Poledne, Rudolf (referee)
At present, the great medicine to develop molecular genetic techniques, which significantly help to explain the causes of illnesses. In some diseases the genetic basis is well known. These are primarily contingent on monogenic diseases. Unfortunately, many diseases remain the genetic cause is still unknown. The largest group is the so-called complex diseases, where the origin and development of disease involving both genetic and nongenetic factors. These diseases include atherosclerosis, diabetes mellitus, orofacial clefts, preeclampsia, neural tube defects, and many others. Complex diseases are serious health and social problem in developed countries. Clasification of risk factors is the subject of much attention, because knowledge of these factors offer opportunities for effective prevention and treatment. The aim of my work was to obtain new knowledge of factors affecting homocysteine metabolism with regard to the formation of some complex diseases in the Czech population.
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Piarists in Beroun
Veselá, Kamila ; Pokorný, Jiří (referee)
Když Josef Kalasánský v roce 1597 otevřel školu při kostele sv. Doroty v římské chudinské čtvrti Trastevere, aby dal římské mládeži, která vyrůstala na ulici a žila stále na pokraji zločinu, šanci na lepší život, udělal tím první krok k vytvoření nového školského řádu, který se měl v budoucnosti rozšířit nejen do dalších zemí, ale i na jiné kontinenty. Jistě tento budoucí světec v životě neslyšel o městě jménem Beroun, do jehož historie tímto svým činem také zasáhl. O 176 let později sem totiž piaristé zavítali a na téměř sto let spojili svůj osud s tímto městem. 116 let po jejich odchodu z Berouna jsem začala navštěvovat 1. základní školu v Berouně já, shodou okolností to byla právě škola, která stojí namístě bývalého působiště piaristů a která v současné době nese jméno Josefa Jungmanna, nejznámějšího žáka berounských piaristů. Okolnostmi okolo příchodu piaristů do Berouna se již dříve zabýval můj otec, který mě k tomuto tématu inspiroval a laskavě mi ho přenechal. Powered by TCPDF (www.tcpdf.org)
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The Economic Impacts of Active Employment Policy
Novotná, Ivana ; Veselá, Kamila (advisor) ; Jitka, Jitka (referee)
The goal of this thesis is to conclude the Active Employment Policy, its tools, advantages and disadvantages and to find an effective solution. The Issue of Unemployment is described continuing with new methods and their utilization in the Czech Republic and then in the Vysocina Region.
One of the biggest issues is a fact that nowadays do not exist any evaluations of the results of tools of effectivity which leads to creating a bias in their benefits for the society. A big part of the state budget goes into expenses of the Active Employment Policy, nevertheless it is not known their progress.
Consistent analyses and controls of using these tools described in this thesis might lead to a solution but another issue can be showed up, e.g. Act No. 101/2000 Coll., on the Protection of Personal Data. It can be theoretically contacted that some of the tools and methods are not as effective as the society needs, on the other hand it is hard to substantiate the real results.
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Collective invesment
Černý, Štěpán ; Veselá, Kamila (advisor) ; Jitka, Jitka (referee)
The main object of this Diploma Thesis is according to collective investment through mutual funds formulate appropriate portfolio model for different types investors of retail banking. Theoretical part of the thesis is focuses on information and rules of investements, advantages and disadvanteges of collective investmentm fund types and their strategies. The practical part parses the selected mutual funds and then compares according to historical performance and riskiness. In the last part of it is handled by the main target. In this section are created model portfolia for individual investors, which are diversified and selected investment companies. Each of the suggestions and recommendations of the model portfolios correspond to the principles of conservative, balanced and dynamic investor.
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Asymmetric Information in the Process of Investing to Funds of Qualified Investors
Veselá, Kamila ; Soukup, Alexandr (advisor) ; Severová, Lucie (referee)
The submitted paper focuses on information asymmetry in the area of investments in qualified investors' funds. The paper focuses on qualified investors' funds in the form of open-end mutual funds that allow the subscription of allotment certificates, i.e. they offer investment opportunities. The nature of qualified investors' funds allows, compared to standard funds, the execution of more venturous investment strategies, which, however, includes much higher risk connected to the information asymmetry. The paper is based on the assumption of information asymmetry between Investment Company and potential investors. The quality of the provided information is therefore critical; however, the investor cannot be expected to have the same knowledge of the fund as does the manager of the fund. The assumption of information asymmetry is based on the differences of interests of Investment Company and potential investor. Investor's interest is to maximize his own profit (net present value), but the interest of Investment Company is to maximize his profit (fee for managing the fund). The manager, maximizing the profit (his fee for managing the fund), may try to contort information towards the investor to "lure" him into an investment and thus achieve his goal. The objective of this dissertation paper is therefore the identification of risks connected to investing in QIF (qualified investors' funds) as result of the existence of IA (information asymmetry) on the side of the investor, qualitative analysis and proposal of measures leading to the elimination of IA. It's meant (in this paper) that information asymmetry is misrepresentation of information and also the incompleteness of information. The results are the basis for two outputs of this paper: investments recommendation for potential investors and information duties recommendation focused for Investment Companies. The aim of these outputs is to eliminate the influence of IA in the process of decision -- making of potential investors.
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Investment decision-making in collective investment
Toman, Lukáš ; Veselá, Kamila (advisor) ; Markéta, Markéta (referee)
The thesis is focused on using instruments of collective investment (mutual funds) for recommendations of more effective financial portfolios of ten real investors. For accomplishing goals of the thesis, firstly it is essential to define basic theoretical knowledge in terms of collective investment or more precissely mutual funds (chapter 2, Theory of collective investment). Subsequently it is necessary to set how will portfolio recommendations be formulated. It is also important to determine key investors characteristics, which are going to effect recommendations (chapter 3, Formulating portfolios). For real contribution it is vital to choose particular mutual funds, which are suitable for recommended portfolios (chapter 4, Selection of mutual funds). Pivotal part of the thesis is the chapter 5, Investment cases, which contains ten real financial portfolios. For each investor is recommended an optimal investment portfolio, which takes into account all known relevant information about the investor. For each case a comparison of current and recommended portfolio is created. The thesis is summarized by the chapter 6, Summary of investment cases, in which a discussion of aggregated results is broken into three areas: the most important investors characteristics, asset allocation of the portfolios and statistical differences between the current and the recommended portfolios.
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Investing on capital markets
Páral, Daniel ; Veselá, Kamila (advisor) ; Srbek, Pavel (referee)
Bachelor thesis Investing on capital markets is divided into theoretical and practical section. Theoretical part contains theoretical basis which is important for subsequent practical part. Practical part describes the creation of three portfolios for conservative investors based on historical data. Portfolios are then subject to analysis which examines their profitability, risk and liquidity. In conclusion all three portfolios are compared and their advantages and disadvantages are mentioned. Main goal of this thesis is to compare three portfolios suitable for a conservative investor and their valuation.
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Financial analysis of selected company
Kubelková, Michaela ; Veselá, Kamila (advisor) ; Srbek, Pavel (referee)
The aim of this Bachelor thesis is based on the selected methods to draw up a financial analysis of the selected business in the five-year period and subsequently evaluate the economic situation. The selected firm was selected company ELFIS spol. s r.o. work is divided into two parts. In the first part are defined by the basic concepts and tools of financial analysis, which serves as the theoretical foundations and supporting documents for the second part of the work. In the second part is the first listed company's characteristic ELFIS spol. s r.o. in which the financial analysis carried out in the years 2010 to 2014. In the practical part of the economic data are processed during the reporting period, and the use of selected indicators of financial analysis is the analysis of the economic situation of the company ELFIS spol. s r.o. Analysis consists of horizontal and vertical analysis, analysis of financial ratios and summary indexes of the guest. In conclusion is a summary on the development of the economic situation of the company during the reporting period.
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