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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Oxidative stress, microinflammation and cardiovascular risk in patients with chronic kidney disease
 Hodková, Magdalena ; Kalousová, Marta (advisor) ; Průša, Richard (referee) ; Racek, Jaroslav (referee)
Chronic kidney disease (CKD) patients are at a significantly higher risk of atherosclerotic complications when compared to the general population. Oxidative stress and the related chronic microinflammation are possible causes of this increased cardiovascular risk, which is most pronounced in patients undergoing chronic haemodialysis (HD) treatment. Oxidative stress in HD patients can be further increased by routine pharmacological interventions (especially by intravenous - i.v. iron preparations administration). The aim of the thesis was to investigate neutrophil respiratory burst and some molecules related to oxidative stress and chronic inflammation - pregnancy-associated plasma protein-A (PAPPA), advanced oxidation protein products (AOPP), C-reactive protein (CRP), intercellular adhesion molecule-1 (ICAM-1) and E-selectin during HD session and to find out whether they can be pharmacologically affected by i.v. ferric sodium-gluconate and oral vitamin E administration. We focused on studying PAPP-A in chronic renal disease (CKD) patients, patients treated with continuous ambulatory peritoneal dialysis (CAPD) and chronic HD patients. We have observed that HD patients' neutrophils are primed to generate greater quantities of superoxide than those of healthy controls. This production decreases during HD and...
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Identification of putative circadian clock cells in a heteropteran insec, Pyrrhocoris apterus
Syrová, Zdeňka ; Hodková, Magdalena ; Doležel, David ; Šauman, Ivo
We identified per expressing cells in compound eyes, pars intercerebralis of brain and corpora cardiaca, while PDH-immunoreactivity was found in lateral neurons between central brain and compond eyes. Removal of the compound eyes resulted in a loss of the circadian rhythmicity
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See also: similar author names
2 HODKOVÁ, Michaela
1 Hodková, Markéta
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