National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Prediction of the replication origin in prokaryotic genomes
Lebó, Marko ; Maděránková, Denisa (referee) ; Sedlář, Karel (advisor)
This bachelor’s thesis deals with the problem of origin of replication (oriC) detection in genomes of prokaryotic organisms. It describes the differences in the processes of initiation of replication in organism of the both procaryotic domains – Bacteria and Archea. It describes the possibilities of conversion of DNA sequences into their numeric representaions and evaluates their application for oriC detection. Also, it describes different approaches in oriC detection and describes te functioning of already present programmes for oriC detection. Finally, it suggests a new tool for oriC detection in bacterial genomes – FindOri and discusses results, achieved during the testing of this tool.
Prediction of the replication origin in prokaryotic genomes
Lebó, Marko ; Maděránková, Denisa (referee) ; Sedlář, Karel (advisor)
This bachelor’s thesis deals with the problem of origin of replication (oriC) detection in genomes of prokaryotic organisms. It describes the differences in the processes of initiation of replication in organism of the both procaryotic domains – Bacteria and Archea. It describes the possibilities of conversion of DNA sequences into their numeric representaions and evaluates their application for oriC detection. Also, it describes different approaches in oriC detection and describes te functioning of already present programmes for oriC detection. Finally, it suggests a new tool for oriC detection in bacterial genomes – FindOri and discusses results, achieved during the testing of this tool.

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