National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Signal transduction in olfactory sensory neurons of vertebrates and tools for the computer simulation
Beneš, Martin ; Zápotocký, Martin (advisor) ; Hejnová, Lucie (referee)
The purpose of this thesis is summing up the information about olfactory transduction of vertebrates. This review is divided into four parts, each part focuses on a different aspect of olfactory transduction. First there is an overview of basic electrophysiological methods used for transduction research, followed by a description of a complete transduction on a molecular level. Next is a summary of model types and their use in olfactory transduction simulation, including a detailed description of two models: One of them describes the beginning of olfactory transduction, from the odorant binding on the receptor to the cAMP production, the other deals with the negative feedback of Ca2+. Finally there is an overview of software products designed to create and analyze the models from the preceding section.
Signal transduction in olfactory sensory neurons of vertebrates and tools for the computer simulation
Beneš, Martin ; Zápotocký, Martin (advisor) ; Hejnová, Lucie (referee)
The purpose of this thesis is summing up the information about olfactory transduction of vertebrates. This review is divided into four parts, each part focuses on a different aspect of olfactory transduction. First there is an overview of basic electrophysiological methods used for transduction research, followed by a description of a complete transduction on a molecular level. Next is a summary of model types and their use in olfactory transduction simulation, including a detailed description of two models: One of them describes the beginning of olfactory transduction, from the odorant binding on the receptor to the cAMP production, the other deals with the negative feedback of Ca2+. Finally there is an overview of software products designed to create and analyze the models from the preceding section.

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