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National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
The development and maintenance of neurons in the inner ear
 Wirthová, Natália ; Pavlínková, Gabriela (advisor) ; Pysanenko, Kateryna (referee)
Hearing loss is among the most frequent disabilities. Neurosensory hearing loss is permanent and results from the death of neurons or sensory cells, which have little ability to regenerate in the inner ear (cochlea). Identifying the genes that are associated with generating differentiated and functional sensory cells, neurons, and with hearing loss could provide tools for neurosensory regeneration therapy and preventive measures. Recent data suggest that the prevention of neuronal loss and enhancement of long- term maintenance of neurons are the most important targets for the immediate future. This work is focused on transcription factors and signaling pathway networks that regulate the development and maintenance of neurons in the inner ear.
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