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National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Migration and homing of mesenchymal stem cells.
 Porkertová, Michaela ; Tlapáková, Tereza (advisor) ; Turnovcová, Karolína (referee)
Mesenchymal stem cells (MSCs) are multipotential progenitor cells derived from the mesodermal germ layer of vertebrate embryos. These cells are able to differentiate in different cell types, such as adipocytes, chondrocytes, osteocytes and others. The differentiation potential of MSC is closely related to their other abilities, with immune system regulation and regeneration of damaged tissues. After injury, MSCs migrate to affected areas where they supress the immune response and reduce inflammation. MSCs also promote regeneration of the affected area by differentiating in cell types according to the actual needs of the organism. This brings us to the most important attribute of MSCs, namely their migratory potential. MSCs are able to migrate across the body using the bloodstream and into the tissues through complicated mechanism using many factors. The aim of this thesis is to prepare a comprehensive review of current knowledge about MSCs, their migration and homing.
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See also: similar author names
1 Porkertová, Martina
2 Porkertová, Monika
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