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National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Glucose homeostasis in the perinatal period and its influence on early psychomotor development of children of diabetic mothers
 Tabery, Kryštof ; Štechová, Kateřina (advisor) ; Korček, Peter (referee) ; Macko, Jozef (referee)
THE EFFECT OF THE PERINATAL GLUCOSE HOMEOSTASIS ON THE EARLY NEURODEVELOPMENT IN INFANTS OF DIABETIC MOTHERS. Abstract This dissertation is presenting a novel approach in a screening of neonatal hypoglycaemia by continuous glucose monitoring (CGM) in neonates of mothers with diabetes. Neonatal hypoglycaemia is one of the most common neonatal pathologies and may adversely affect the neurodevelopment and may also have serious acute complications. Current standard approach for preventing neonatal hypoglycaemia is screening by intermittent sampling of glycemia. Blood lettings are an invasive procedure that disrupts the comfort of the newborn and mother - child dyad, more over that it has local risks, and may miss the blood glucose troughs between the sampling. CGM offers a detailed insight into the adaptation of glucose homeostasis while being less invasive. The main objectives of our study were firstly to measure the accuracy of the CGM used as a screening tool in the well baby nursery. Secondly, we evaluated the number of blood samples required due to the use of CGM compared to conventional screening. Thirdly, we assessed the neurodevelopment of our patients using Bayley scales of infant and toddler development. We analysed 43 infants of diabetic mothers. The results showed that CGM can be used as a screening...
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