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Development and optimization of ointment preparation for burn healing
Müllerová, Kristýna ; Sedláček, Petr (referee) ; Enev, Vojtěch (advisor)
This bachelor's thesis aims to prepare ointments based on an ointment base with the addition of a bioactive component of chlorophyll according to a recipe from an unknow doctor. The basic characteristic of emulsions was performer in the theoretical part, their instability and possible methods of stabilization were described. Furthermore, the reader is acquainted with the bioactive substance of chlorophyll, selected ointments for the healing of burns and wounds and finally with the use in medicine. In the Experimental part, the preparation of emulsion bases of ointment was described. Based on a performed analysis of stability using analytical centrifuge, two ointments bases were selected, to which other components were added – chlorophyll, beeswax, and chamomile extract. The stability of completely prepared ointments was studied at 25 °C and 37 °C, this analysis was performed even after a longer time interval. Using ATR-FTIR spectrometry the present functional groups were identified at prepared ointments, individual components of the ointments base and chlorophyll. Based on the stability measurement of the prepared ointments and rheological measurements (oscillation and rotational measurements), it was evaluated that the best properties were shown by the prepared ointment with an ointment base consisting of 30 wt. % white vaseline and 70 wt. % synderman.
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The long-term stability and properties of a skin cream with addition of liposomes
Müllerová, Kristýna ; Pekař, Miloslav (referee) ; Enev, Vojtěch (advisor)
The aim of the thesis was to design a formulation and subsequently prepare a native skin cream and skin creams enriched with liposomal particles with encapsulated vitamin E. After preparation of the skin creams, their stability and rheological properties were studied at given time intervals during storage for 12 weeks. The stability of the prepared samples was determined using a LUMiSizer analytical centrifuge with STEP-Technology. Among the rheological properties, changes in the rate of structure recovery of the formulations were monitored, as well as changes in zero and infinite viscosity, which can be presented as changes in viscosity during product storage and changes in viscosity during application and spreading on the skin. All stability and rheological tests were performed for a temperature of 25 °C, which also corresponded to the storage temperature, and for a temperature of 37 °C, which approximately corresponds to the human body temperature. According to the results, the sample without the addition of liposomes showed the highest stability and the skin cream with the addition of 10 wt.% liposomes at 1 week of age showed the best spreadability. Next, the characterization of liposomal particles was performed. Finally, a sensory analysis was performed where the evaluators compared the fresh native skin cream, the native skin cream at 12 weeks of age, the fresh skin cream with the highest liposome content and the skin cream with the highest liposomal particle content at 12 weeks of age.
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Development and optimization of ointment preparation for burn healing
Müllerová, Kristýna ; Sedláček, Petr (referee) ; Enev, Vojtěch (advisor)
This bachelor's thesis aims to prepare ointments based on an ointment base with the addition of a bioactive component of chlorophyll according to a recipe from an unknow doctor. The basic characteristic of emulsions was performer in the theoretical part, their instability and possible methods of stabilization were described. Furthermore, the reader is acquainted with the bioactive substance of chlorophyll, selected ointments for the healing of burns and wounds and finally with the use in medicine. In the Experimental part, the preparation of emulsion bases of ointment was described. Based on a performed analysis of stability using analytical centrifuge, two ointments bases were selected, to which other components were added – chlorophyll, beeswax, and chamomile extract. The stability of completely prepared ointments was studied at 25 °C and 37 °C, this analysis was performed even after a longer time interval. Using ATR-FTIR spectrometry the present functional groups were identified at prepared ointments, individual components of the ointments base and chlorophyll. Based on the stability measurement of the prepared ointments and rheological measurements (oscillation and rotational measurements), it was evaluated that the best properties were shown by the prepared ointment with an ointment base consisting of 30 wt. % white vaseline and 70 wt. % synderman.
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THE INFLUENCE OF AFRICAN AMERICAN CULURE IN MODERN DANCE
Müllerová, Kristýna ; DIATTA-REBCOVÁ, Monika (advisor) ; OVSOVÁ, Libuše (referee)
This thesis summarizes the history of colonization of the United States
of America, that was the main cause of its current diverse ethnic composition. It
reveals political, social and cultural environment, in which afro-american dance
style has been developed. One direction of this development searched for means
of expression for stage performances. These concepts were influenced
by Katherine Dunham, who has discovered the principles and roots of afroamerican
dancing patterns by combining her interests in anthropology, ethnology
and dancing. She identified herself with these principles a based her own art
work upon them. At the same time, she found new sources of inspiration
by examination of human nature and human origins, which can be used
in modern pedagogical practices.
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