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Microprocessor Controlled Power Measurement System for Frequencies below 10GHz
Klíma, Martin ; Lukeš, Zbyněk (referee) ; Urbanec, Tomáš (advisor)
The aim of this work is to design a microprocessor controlled power measurement system which is based on the logarithmic detector AD8317, then to create a printed circuit board and to test its functioning. The logarithmic detector AD8317 is acceptable for measurement of high frequency signal’s power of the level between approx. –55 dBm and – 3 dBm in the frequency bandwidth of 1 MHz to 10 GHz. Its output provides DC voltage which is corresponding to the decibel-scaled level of the input signal. This is suitable for A/D conversion and digital processing by the microprocessor. The result of the work is a complete measurement system.
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Non conventional applications of HIC´s
Klíma, Martin ; Jankovský, Jaroslav (referee) ; Szendiuch, Ivan (advisor)
This thesis deals with non-conventional applications in the area of thick film technology, especially with indication of the temperature by thermodynamic sensors. The work summarizes thermodynamic sensors theory and also contains production data of the universal thermodynamic sensor realized on ceramic substrate, including measurement of its parameters and heat radiation.
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Universal timer for sport activity
Janůš, Tomáš ; Klíma, Martin (referee) ; Macháň, Ladislav (advisor)
This bachelor thesis deals with a proposal and implementation of wireless electronic time measurement. In the thesis a proposal and implementation of simple wireless time measurement is described. Its part is also a proposal and creating of the optical barrier. The theoretical part further contains description and usage of various sensors. All sensors are wirelessly interconnected with the main device. The time measurement is being processed in the computer by means of a created programme which enables to control the time measurement and to save measured times as well.
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Design of steam generator tube bundle
Klíma, Martin ; Lošák, Pavel (referee) ; Nekvasil, Richard (advisor)
Diploma thesis is focused on analisis of the steam generator tube bundle on the basis calculation by the finite elements method and softwaru ANSYS. Next it will also také account of job descriptions and methods of operation of the equipment propřed plan revision kontrol points that will be most critical. Annexes included documentary of model from the SolidWorks.
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The lamination of Low Temperature Co-fired Ceramic
Hudeček, Ondřej ; Klíma, Martin (referee) ; Kosina, Petr (advisor)
Master’s thesis deals with the optimalization of low-temperature cofired ceramic lamination process that affects the final quality of 3D structures (eg., channels, cavities, membranes, etc.). The paper evaluates the influence of lamination parameters (pressure, temperature, time) on the formation of defects in the structure, which were detected by appropriate methods. The last parts describes designed and simulation cooling water system using LTCC technology.
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Personal communicator for strategic sports
Válik, Martin ; Klíma, Martin (referee) ; Macháň, Ladislav (advisor)
The aim was to design connept of personal communicator useable for strategic sports such as airsoft or painball. Personal communicator provide wireless transmission of position provided by GPS module, eventually other data via RF module. Interactive user interface is solved by TFT touch display. For controlling of modules is used 32-bit ARM based microcontroller. The output is demonstration of functionality of communication and vizualization of distance between two designed devices on TFT display.
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History of education in Zliv
KLÍMA, Martin
This bachelor thesis deals with the history of an elementary school in Zliv in 1889-1945. The introduction is focused on the history of the town and the history of education in Zliv. Due to the complexity of this topic, this thesis is focused only on a primary school in Zliv. The core of this thesis is comprised of two chapters, which are focused on the life at Zliv's primary school in the pre-war, interwar and war periods. This work describes the teaching staff and the headteachers who worked at school in the given period. Furthermore, it deals with the pupils and their school education in the given period. This work also includes important events which influenced the school's activity. The last topics, which this thesis deals with, are regular school events and celebrations. This bachelor thesis is mainly based on school chronicles and chronicles of the town.
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The role of inactive MTMR phosphatases in mammalian cells
Sixtová, Nikola ; Macůrková, Marie (advisor) ; Klíma, Martin (referee)
Variable composition of the cellular membranes influences many cellular events such as endosomal transport, autophagy or cellular signalling. The membrane identity is significantly determined by the specific distribution of phosphoinositide derivatives. These derivatives are specifically distributed among cellular membranes and they are tightly regulated by the interplay of corresponding lipid kinases and phosphatases. Myotubularins (MTMRs) form a family of phosphatases dephosphorylating phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate at the 3rd position of the inositol ring. Similarly to their substrates, MTMRs are involved in various cellular events such as endosomal transport or autophagy. Mutations in MTMR proteins lead to dysregulation of the cellular events and manifestation of severe pathologies. Among the most studied are two hereditary diseases, X- linked myotubular myopathy and Charcot-Marie-Tooth syndrome, caused by mutations in MTM1 and MTMR2 genes, respectively. One of the specific features of the MTMR family is the presence of catalytically inactive members. These members were found to regulate protein stability, activity and localization of their active partners. MTMR10 and MTMR12 are two inactive members of the MTMR family, directly interacting with the...
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Molecular and functional characterization of the death receptor 6
Klíma, Martin ; Anděra, Ladislav (advisor) ; Živný, Jan (referee) ; Kovář, Marek (referee)
Death receptor-6 (DR6/TNFRsf21/CD358) is a receptor from the TNFR superfamily that likely participates in the regulation of proliferation and differentiation of T- and B-lymphocytes and neural cells. The 655-amino acid human DR6 is a type I transmembrane protein containing four cysteine-rich domains in its extracelular part and a death domain followed by the CARD-like region in its cytoplasmic part. Overexpression of DR6 in some cell lines leads to apoptosis, and/or to activation of nuclear factor NF-κB and stress kinases of the JNK family. In the first part of our work we focused on molecular characterization of DR6, including the analysis of its posttranslational modifications. We found that DR6 is an extensively posttranslationally modified protein including S-palmitoylation and both N- and O-glycosylation. Six N-glycosylation and one S-palmitoylation sites were precisely mapped to appropriate asparagines and cysteine respectively. The juxtaposed linker region (between cystein-rich domains and the transmembrane part), which also contains Ser/Thr/Pro-rich region with clustered putative O-glycosylation sites, is required for the plasma membrane localization of DR6. N-glycosylation, but interestingly not S-palmitoylation, may play a role in targeting of DR6 into detergent-resistant...
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Molecular and functional characterization of the death receptor 6
Klíma, Martin
Death receptor-6 (DR6/TNFRsf21/CD358) is a receptor from the TNFR superfamily that likely participates in the regulation of proliferation and differentiation of T- and B-lymphocytes and neural cells. The 655-amino acid human DR6 is a type I transmembrane protein containing four cysteine-rich domains in its extracelular part and a death domain followed by the CARD-like region in its cytoplasmic part. Overexpression of DR6 in some cell lines leads to apoptosis, and/or to activation of nuclear factor NF-κB and stress kinases of the JNK family. In the first part of our work we focused on molecular characterization of DR6, including the analysis of its posttranslational modifications. We found that DR6 is an extensively posttranslationally modified protein including S-palmitoylation and both N- and O-glycosylation. Six N-glycosylation and one S-palmitoylation sites were precisely mapped to appropriate asparagines and cysteine respectively. The juxtaposed linker region (between cystein-rich domains and the transmembrane part), which also contains Ser/Thr/Pro-rich region with clustered putative O-glycosylation sites, is required for the plasma membrane localization of DR6. N-glycosylation, but interestingly not S-palmitoylation, may play a role in targeting of DR6 into detergent-resistant...
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