|
|
Default Mode Network: Ontogeny
Jarmar, Jiří Kryštof ; Nekovářová, Tereza (advisor) ; Moravcová, Simona (referee)
Default mode network is a functional network system in a brain, comprising of other sub- components. It is activated during tasks focused on the inner monologue, mentalization, episodical memory or self-reflection. The DMN activity is generally described as default mode functioning of the brain in absence of external stimuli, on the other hand its activity is inhibited during the presence of it. This thesis focuses on the main factors and changes that occur during ontogeny of DMN from birth to adulthood, mainly in structural and functional connectivity and anticorrelation relationships with other brain networks. After a general characterization of DMN, the first part focuses on general characterization of functional brain networks and statistical methodology of measuring their relationships and maturity. It follows by the description of important events in brain development and identification of main anatomical regions of DMN. The most important part is the last one, which provides observations of comparative studies of DMN between children and adults. Here we describe main changes and trends in ontogeny of DMN. Key words: Default mode network, functional network, fMRI, ontogeny
|
guest ::
