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Rheological properties of the scar treatment gels
Flanderková, Michaela ; Šnejdrová, Eva (advisor) ; Dittrich, Milan (referee)
1 ABSTRACT Charles University, Faculty of Pharmacy in Hradci Králové Department of Pharmaceutical Technology Candidate Mgr. Michaela Flanderková Consultant PharmDr. Eva Šnejdrová, Ph.D. Title of Rigorous Thesis Rheological properties of gels This thesis deals with evaluation of rheological and adhesion properties of the gels using rotational rheometer. The theoretical part outlines the characterization of gels and their rheological properties, and there is brief information on scars and their treatment options. The principles of the rotational, oscillation, and adhesive tests carried out in the experimental section are also listed. The commercial gels with different composition, type and place of application (Fenistil gel, Voltaren Forte gel, Nexcare gel, Vidisic gel, Strataderm) as well as two newly formulated scar healing gels were evaluated. The results of the rotation tests reveal that the gels with high consistency show the bigger viscosity decrease in comparison to the gels with lower consistency. The oscillation tests are more suitable as the samples are less exposed to a stress. The relaxation strength K* and relaxation exponent n* are the exact characteristics of rheological behaviour of the gels. Only the Nexcare a Scar treatment gel B showed a low relaxation strength and at the same time the low...
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Rheological properties of the scar treatment gels
Flanderková, Michaela ; Šnejdrová, Eva (advisor) ; Dittrich, Milan (referee)
1 ABSTRACT Charles University, Faculty of Pharmacy in Hradci Králové Department of Pharmaceutical Technology Candidate Mgr. Michaela Flanderková Consultant PharmDr. Eva Šnejdrová, Ph.D. Title of Rigorous Thesis Rheological properties of gels This thesis deals with evaluation of rheological and adhesion properties of the gels using rotational rheometer. The theoretical part outlines the characterization of gels and their rheological properties, and there is brief information on scars and their treatment options. The principles of the rotational, oscillation, and adhesive tests carried out in the experimental section are also listed. The commercial gels with different composition, type and place of application (Fenistil gel, Voltaren Forte gel, Nexcare gel, Vidisic gel, Strataderm) as well as two newly formulated scar healing gels were evaluated. The results of the rotation tests reveal that the gels with high consistency show the bigger viscosity decrease in comparison to the gels with lower consistency. The oscillation tests are more suitable as the samples are less exposed to a stress. The relaxation strength K* and relaxation exponent n* are the exact characteristics of rheological behaviour of the gels. Only the Nexcare a Scar treatment gel B showed a low relaxation strength and at the same time the low...
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Influence of increased aplication of the file polyunsaturated fatty acids on alteration of level cholesterol of individuum.
FLANDERKOVÁ, Michaela
I have engaged in the influence of increased aplication of the file polyunsaturated fatty acids on alteration of level cholesterol of individuum in my bachelory work. At first I had studied theoretical knowledge focused the theme of polyunsatureted fatty acid and cholesterol. I had devoted to this knowledge in theoretical part of my bachelory work. After I had contacted some people. I had known that they have increased cholesterol level. This people I had acquainted with themes of my bachelory work and development of research. The acquainted people have accepted part of research. Initial measuring taked place after. The measuring determined the level of total cholesterol, LDL cholesterol, HDL cholesterol, triacylglycerol. The three month interventionist program taked place after, from march 2011 to december 2012. The Participant of research had consumed of food supplement, which contented fish oil. Fish oil is rich in content of polyunsaturated fatty acid omega 3 (EPA and DHA). Output measuring taked place after three month. On the basis of measuring got results. I worked with results in the practical part of my bachelory work. I have compared results of initial and output measuring.
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