National Repository of Grey Literature 3 records found  Search took 0.00 seconds. 
The Evaluation of the Financial Situation’s Company
Brázdová, Andrea ; Adam, Zbyněk (referee) ; Pavláková Dočekalová, Marie (advisor)
Bachelor thesis focuses on the evaluation of the financial situation of the company Ptáček – velkoobchod, a.s. in years 2010-2014 using selected methods of financial analysis. The first part of the thesis describes the theoretical bases, which are applied in the second part on the analysed company. On the basis of findings from the financial analysis, I have proposed measures to improve the financial situation of the company.
Extracellular vesicles and middle T antigen of mouse polyomavirus
Kropáček, Václav ; Šroller, Vojtěch (advisor) ; Brázdová, Andrea (referee)
This study is focused on middle tumor antigen (MT Ag) of mouse polyomavirus (MPyV), potential consequences of it's secretion via extracellular vesicles (EVs) and it's effect on cellular signaling. MT Ag is membrane bound protein able to induce cellular transformation thanks to it's ability to interfere with cellular signal transduction. Mainly due to aberrant activation of MAP kinase pathway. Firstly we followed up previous observations of our group concerning ability of MT Ag to be secreted from cells via extracellular vesicles. We were interested if MT Ag could contribute to malignant transformation in recipient cells. We performed 2 types of EVs isolation from cell lines stably expressing middle T antigen (3T6MT). We confirmed presence of MT Ag in isolated EVs. Then we characterized isolated EVs by detection of exosomal markers and cryo-electron microscopy. In next step we exposed recipient cell line (3T6) to isolated EVs and with use of flow cytometry tried to detect internalization of MT Ag. Simultaneously we tried asses levels of Erk phosphorylation in 3T6 cells exposed to EVs. Secondly we tried to confirm and analyse previous unpublished observations of elevated levels of NF-kB phosphorylation in cells stably expressing MT Ag. We used western blot and detection of NF-kB dependent secreted...
The Evaluation of the Financial Situation’s Company
Brázdová, Andrea ; Adam, Zbyněk (referee) ; Pavláková Dočekalová, Marie (advisor)
Bachelor thesis focuses on the evaluation of the financial situation of the company Ptáček – velkoobchod, a.s. in years 2010-2014 using selected methods of financial analysis. The first part of the thesis describes the theoretical bases, which are applied in the second part on the analysed company. On the basis of findings from the financial analysis, I have proposed measures to improve the financial situation of the company.

See also: similar author names
2 BRÁZDOVÁ, Aneta
2 Brázdová, Aneta
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