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Optimizing and Evaluating the Biocompatibility of Fiber Composites with CaP Additives
Suchý, Tomáš ; Sucharda, Zbyněk ; Balík, Karel ; Sochor, M. ; Bačáková, Lucie
Composite materials based on a polyamide fabric (aramid) and a polydymethyl-siloxane (PDMS) matrix were designed for application in bone surgery. In order to increase the bioactivity, 2, 5, 10, 15, 20 and 25 vol. % of nano/micro hydroxyapatite (HA) and tricalcium phosphate (TCP) were added. The effect of the additives on the biocompatibility was studied. It appears that nano additives have a more favorable effect than micro particles on mechanical properties. For final application of the composites as substitutes for bone tissues, 15 vol. % of nano hydroxyapatite additives is an optimum amount: in this case both the mechanical properties and the biological properties are optimized without distinct changes in the inner structure of the composite.
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Biocompatibility optimization of fabric composites by calcium phosphates
Sochor, M. ; Balík, Karel ; Suchý, Tomáš ; Sucharda, Zbyněk
Composite materials based on a polyamide fabric and a polydimethylsiloxane matrix were designed for application in bone surgery. In order to increase the bioactivity, 2, 5, 10, 15, 20 and 25 vol. % of nano/micro hydroxyapatite and tricalcium phosphate were added. The effect of the additives on the mechanical properties was studied. Simultaneously, changes in the inner structure of the composites were investigated by means of image analysis.
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Some surface improvement and osseointegration
Suchý, T. ; Balík, Karel ; Sedláček, R. ; Sochor, M.
As a further perspective material to be used in orthopedics, glass fibers (R-glass, 21055 satin-woven fabric, VETROTEX, Saint Gobain, France) and polysiloxane matrix (M130, Lučební závody Kolín, Czech Republic) based composite materials have been investigated.
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Porous composites based on siloxane resin for hard tissue replacements
Suchý, T. ; Balík, Karel ; Sochor, M. ; Černý, Martin ; Hulejová, H. ; Pešáková, V.
A composite material based on polysiloxane and first on glass fabrics was prepared. The composite samples were prepared with controlled open porosity, the sizes of which were in the range: i) 0,2-0,4 mm, ii) 0,4-0,6 mm, and iii) >0,6 mm. For further improvement of osseointegration, a powder hydroxyapatite, particle size of 0,005 mm in the amount of 10 wgt %. The effects of surface treatment and hydroxyapatite matrix additives on osseointegration were studied by methods in vitro and in vivo.
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