National Repository of Grey Literature 3 records found  Search took 0.01 seconds. 
Nanotechnologies in regenerative medicine
Syková, Eva
Magnetic resonance imaging provides a noninvase method to study the fate of transplanted cells in vivo. Various biocomatible scaffolds based on non-woven nanofibres (products of ELMARCO or Technical University Liberec), have been developed for bridging tissue defects and for use as 3D stem cell careiers.
NANOTECHNOLOGY AND BIOMATERIALS IN MEDICINE
Kubinová, Šárka ; Jendelová, Pavla ; Lesný, Petr ; Holáň, Vladimír ; Syková, Eva
Our studies focus on the use of nanotechnology in cell therapy and tissue engineering for the treatment of brain and spinal cord injury, corneal defects and chronic wounds.
Effect of endocrine disruptors on mammalian fertility
Pěknicová, Jana ; Nováková, Vendula ; Buckiová, Daniela ; Boubelík, Michael ; Elzeinová, Fatima ; Kubátová, Alena
Endocrine system is one of the most important regulatory systems in the mammalian body. The endocrine disruptors (ED) can disrupt the function of the endocrine system but their activity is not a result of the physiological regulation. The effect of low dose of selected ED, bisphenol-A (BPA), p-nonylphenol (NP), diethylstilbestrol (DES), genistein (GEN), resveratrol (RES)), hormone (17α-ethynylestradiol (EE2)) and polybrominated compound (tetrabromobisphenol A (TBBPA)) within development of reproductive tract in outbred CD1 mice was tested. BPA and NP had a negative effect on reproductive organs morphology and mouse spermatozoa. The fertility of mice exposed to DES was disrupted. Contrary to that, treatment by GEN and RES had no effect on the fertility of mice but had some effect on their reproductive parameters except for sperm integrity. Synthetic hormone (EE2) and polybrominated compound (TBBPA) also affected on the organ weight, reproductive parameters and sperm quality.

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