Home > Search Results: Živná, Natálie
Search:
Search Tips :: Advanced Search
Search collections:
Sort by: Display results: Output format:
National Repository of Grey Literature 3 records found  Search took 0.00 seconds. 
Synthesis of novel compounds as potential radioprotectives
 Živná, Natálie
Harmful substances polluting the environment, including ionizing radiation, and an unhealthy lifestyle are responsible for the increased incidence of cancer. The projected outlook for the next ten to twenty years suggests an increase of 63% in newly diagnosed cases of cancer annually. Radiotherapy is an important component of cancer treatment, given approximately to 50% of all cancer patients. Despite ongoing advances in the methods of radiotherapy, quality of life continues to be lowered as a result of the radiation treatment. Novel strategies towards improvement need to be adapted, such as the use of radioprotective substances. The goal of this thesis is to synthesize novel radioprotective agents based on the 1-(2- hydroxyethyl)piperazine moiety targeting the intrinsic apoptotic pathway, therefore protecting healthy tissue from ionizing radiation.
Detailed record
Synthesis of novel compounds as potential radioprotectives
 Živná, Natálie ; Hraníček, Jakub (advisor) ; Górecki, Lukáš (referee)
Harmful substances polluting the environment, including ionizing radiation, and an unhealthy lifestyle are responsible for the increased incidence of cancer. The projected outlook for the next ten to twenty years suggests an increase of 63% in newly diagnosed cases of cancer annually. Radiotherapy is an important component of cancer treatment, given approximately to 50% of all cancer patients. Despite ongoing advances in the methods of radiotherapy, quality of life continues to be lowered as a result of the radiation treatment. Novel strategies towards improvement need to be adapted, such as the use of radioprotective substances. The goal of this thesis is to synthesize novel radioprotective agents based on the 1-(2- hydroxyethyl)piperazine moiety targeting the intrinsic apoptotic pathway, therefore protecting healthy tissue from ionizing radiation.
Detailed record
Synthesis and in vitro evaluation of cytotoxic effect of potential decontaminants based on quaternary ammonium salts
 Živná, Natálie ; Martínková, Markéta (advisor) ; Hraníček, Jakub (referee)
Detailed record

Interested in being notified about new results for this query?
Subscribe to the RSS feed.
Digital Repository :: Search :: Submit :: Personalize :: Help
Powered by Invenio v1.1.2
Maintained by admin.invenio@techlib.cz
This site is also available in the following languages:
Česky  English