Home > Search Results: recid:295871
Search:
 
Search Tips :: Simple Search
Search collections:
Sort by: Display results: Output format:
National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 

(100)
Recently active L1 and B1 retrotransposons in the mouse genome
 Janoušek, Václav ; Munclinger, Pavel (advisor) ; Bryja, Josef (referee)
The work focuses on two recently active retrotransposon families in the house mouse genome. They are L1 and B1 retrotransposons. The aim of the work was to find polymorphic retrotransposon insertions caused by their recent activity. Two genomes of mouse inbred strains derived from the different house mouse subspecies were compared. The BACends from MSM/Ms derived from M. m. molossinus were compared with the reference genome of C57BL/6J derived mostly from M. m. domesticus. The set of output insertions was classified into several subfamilies of B1 a L1 families. The presence/absence of these insertions was tested using PCR in all three house mouse subspecies and also in two sister species (M. spretus and M. macedonicus). The particular subfamilies differed with regard to presence in latter species. Despite the supposed lack of activity of older L1 families (F2 and F3) they persist in house mouse population as an ancestral polymorphism. Unlike L1 subfamilies, B1 subfamilies appear to be active in house mouse genome for longer period of time. Also the difference between the whole families L1 and B1was observed. Thus, according to my data L1 family seems to be recently more active than B1 family.
Detailed record

Interested in being notified about new results for this query?
Subscribe to the RSS feed.
Digital Repository :: Search :: Submit :: Personalize :: Help
Powered by Invenio v1.1.2
Maintained by admin.invenio@techlib.cz
This site is also available in the following languages:
Česky  English