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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Type II secretion system in gram negative bacteria.
 Klápšťová, Veronika ; Doležal, Pavel (advisor) ; Mach, Jan (referee)
This thesis describes the structure and the assembly of the type II secretion system which is found in some gram negative bacteria such as Vibrio cholerae, Pseudomonas aeruginosa, Legionella pneumophila or Klebsiella oxytoca and which transports their exoproteins across the outer membrane. The thesis also presents some important substrates translocated by this system - toxins, enzymes and proteins involved in bacterial metabolism or motility - and hypothetical mechanism of the secretion. Conclusion is focused on the discovery of the secretion system in mitochondria of some protists and its importance for the research of the evolution of eukaryotic organisms.
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Understanding the role of bb0454 during infection by Borrelia afzelii
 HAIN, Lisa
The aim of this thesis was to further our understanding of the importance of bb0454, a gene located at the linear chromosome of the Borrelia genome, which encodes a glycosyltransferase catalyzing the synthesis of one of the major glycolipids found in the outer membrane of this pathogenic bacteria.
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