National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Role of queuosine tRNA modification in the parasitic protist \kur{Trypanosoma brucei}
KULKARNI, Sneha Sunil
This study analyzes the queuosine (Q) tRNA modification and the enzyme responsible for Q formation, the tRNA guanine transglycosylase (TGT), in the parasitic protist \kur{Trypanosoma brucei}. We describe the interdependence of Q modification and tRNA subcellular trafficking, and how these two factors regulate codon biased translation. The effect of Q on translation has serious implications in the virulence of the parasite inside the mammalian host.

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