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Research study of mechanical properties of cranial tissue
Wojtek, Lukáš ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
This bachelor thesis deals with the problematics of determining mechanical properties of cranial bone tissue. In this thesis a search study associated with an experimental determination of mechanical properties of bone tissues is executed. A brief history and progress of imaging methods and their importance of computation modelling are introduced. There are descriptions of histomorfometric parameters describing a structure of bone tissue at the micro level, ways of their computation and their impact on mechanical properties of bone tissue. Practical part of the thesis is focused on processing micro-CT images of cranial bone as well as analysing histomorfometric parameters (BV/TV, TbTh, TbSp) and subsequently stress strain analysis of selected sections of cranial bone tissue. Resulting Young´s modulus of elasticity of bone tissue [MPa] are compared with results from experiments from literature.
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Biomechanical Study of Hand
Krpalek, David ; Janíček, Přemysl (referee) ; Horyl, Petr (referee) ; Florian, Zdeněk (advisor)
This work deals with issue of human wrist and appropriate total wrist implant allowing a restoration of hand mobility approaching physiological condition after traumatic and degenerative diseases. Treating these diseases are very complex. These issues including a biological and medical issues. To determine the appropriate treatment method and select right total wrist implant is important to know the behavior the human wrist at all stages in terms of medical and biomechanical. For this reason, it was developed a biomechanical study including computation model of human wrist allowing solution of strain and stress of hand in physiological and pathological conditions and condition after total wrist implant. The frost remodeling of bone tissue was used for analysis of human wrist bone tissues and bone tissues after application of total wrist implant RE-MOTION™ Total Wrist.
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Stress-strain analysis of mandible with applied fixator due to the missing bone tissue
Fňukal, Jan ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
This thesis deals with the fixation of lower jaw with bone tissue defect using commercially produced fixator. Large defects of bone tissue are mainly caused due to the removal of bone tissue affected by tumor. These topics have been researched on the basis of the literature. Subsequently, stress strain analysis of the lower jaw with the applied fixation plate was performed. This analysis was solved by using computational modeling with variational approach, ie the finite element method. The work also describes in detail the procedure of creating model of geometry, model of material, model of boundary conditions and loads with subsequent solution of several computational models. The stress strain analysis was done for lower jaw with varying size of the removed bone tissue with applied reconstruction plate made of CP-Ti Grade 4 and for the lower jaw with the plate, which is made of -Ti-Mo. Finally, the influence of the mechanical properties of the callus during formation of new bone tissue (callus healing) on the stress and deformation of the solved system was evaluated.
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Biomechanical Studies of Facial Bone
Valášek, Jiří ; Janíček, Přemysl (referee) ; Horyl, Petr (referee) ; Florian, Zdeněk (advisor)
Presented work deals with Biomechanical study of the facial skeleton. This work is focused on the fixation of the mandible after removal of a tumor from affected bone tissue. The aim of the work is to perform biomechanical study of the facial skeleton with subsequent detailed stress strain analysis of two mandible implants designed and manufactured for specific patients. The geometry model of mandible used for design of mandible implants and used for computational modelling has been obtained on the basis of CT data of two patients. A Theoretical-Clinical sub-study that deals with the comparison the CT data processing which is necessary for creating the model of geometry is a part of the thesis. Two models of mandible with applied mandible implant have been created for two specific patients with tumorous mandible bone tissue. Stress strain analysis has been performed for these two models. Results of the stress strain analysis of two models of mandibles with mandible implants are presented in the final chapters of the thesis. Findings of the biomechanical study have been published and applied in clinical practice.
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The role of imaging techniques in creation of computational models in biomechanics.
Prášilová, Eva ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
The first part of the bachelor´s thesis is dealt with the processing history of imaging techniques and their indications in a clinical practice. From point of view of the computer modeling, the computer tomography plays an important role in biomechanics. The second part of this treatment describes the scan processing of sections of two human mandible obtained from computer CT and micro-CT tomography. As a non-invasive way procedure can be characterized the image processing techniques, which analyze a bone density and BVF. The manual segmentation was applied in this analysis provided in ROI analysis software. There are shown the graphs of the bone densities of segments of two human mandibles depending on the specimen length and also there are compared the results of the measurements received from the CT and micro-CT tomography. Then follow the results illustrating the correlation of the relations and recalculations, which can be used as the determination tool of the mechanical properties of bone tissue. Finally there are described the computer models created in ANSYS focused on the different bone density analysis and stress strain analysis.
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Determination of mechanical properties of cancellous bone tissue of skull bone
Votava, Tomáš ; Borák, Libor (referee) ; Marcián, Petr (advisor)
This bachelor thesis is focused on determination of mechanical properties of cancellous bone tissue of cranial bone. In research part of this study are described methods of medical imaging, mechanical properties of cranial bone tissue and anotomy of skull. Next one are described studies focused on determination mechanical properties of cancellous bone. Finally are decribed histomorphometric parameters and their measurement using software I$mageJ2$ and plugin $BoneJ2$. In practical part of this thesis, there are described measurement procedure, measurement results, 3D geometry modelling procedure by reconstruction micro-CT images and determination of mechanical properties solved by computational modeling using FEM. Five speciments are analyse predominantly from os occipitale. On first specimen is analyzed influence of thresholding settings.
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Biomechanical Study of Tooth Implants for Low Density Bone
Marcián, Petr ; Janíček, Přemysl (referee) ; Horyl, Petr (referee) ; Florian, Zdeněk (advisor)
This work deals with problem of dental implant area, where there are many problems at the dental implants application. The essential issue is the bone tissue quality at implant application, which sig-nificantly influences its deformation, tension and the possibility of subsequent implant failure. The knowledge of bone tissue mechanical properties of mandible and mandible with applied implant can significantly affect prediction of dental implant failure. The mechanical interaction can be described by variable determining deformation and tension of solved system. For this reason the computational modeling by using Finite Element Method was used for solving given problem. The computational model creation of solved system on the high resolution level is necessary for biomechanical assessment of implant failure, including bone tissue quality. For this purpose the biomechanical study was performed, which significantly spreads range of solved problem in this work afterwards. In this work the methodology, which describes assessment of bone tissue quality where the implant should be applied as well as mutual interaction, is presented. The results confirm necessity of bone tissue computational models creation on high resolution level including complex trabecular architecture. In this work the creation of trabecular structure computational model from data gained on micro-CT device is described. Further, the trabecular structure computational model was created on the 3D level with dental implant and the stress strain analysis was performed consequently. The last part of this work deals with introductory study of bone tissue modeling and remodeling.
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Estimation of mechanical properties of the cancellous bone tissue of the proximal tibia
Leinweber, Vít ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
This bachelor thesis is focused on the determination of mechanical properties of cancellous bone tissue of proximal tibia. In the beginning of the work there is theoretical part which consists of a description of the tibia anatomy from macroscopic and microscopic view, treatise on the bone tissue growth, influences affecting the bone tissue growth and description of mechanical properties of the bone tissue. In the end of the theoretical part there is a detailed review of related literature to this work. In the practical part morphometric parameters are measured using software ImageJ and plugin BoneJ. The process of creating a computational model is described and results of mechanical properties are presented. Regression models of mechanical properties and histomorphometric parameters are created from these results.
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Estimation of mechanical properties of the cancellous bone tissue of the proximal tibia
Leinweber, Vít ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
This bachelor thesis is focused on the determination of mechanical properties of cancellous bone tissue of proximal tibia. In the beginning of the work there is theoretical part which consists of a description of the tibia anatomy from macroscopic and microscopic view, treatise on the bone tissue growth, influences affecting the bone tissue growth and description of mechanical properties of the bone tissue. In the end of the theoretical part there is a detailed review of related literature to this work. In the practical part morphometric parameters are measured using software ImageJ and plugin BoneJ. The process of creating a computational model is described and results of mechanical properties are presented. Regression models of mechanical properties and histomorphometric parameters are created from these results.
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Determination of mechanical properties of cancellous bone tissue of skull bone
Votava, Tomáš ; Borák, Libor (referee) ; Marcián, Petr (advisor)
This bachelor thesis is focused on determination of mechanical properties of cancellous bone tissue of cranial bone. In research part of this study are described methods of medical imaging, mechanical properties of cranial bone tissue and anotomy of skull. Next one are described studies focused on determination mechanical properties of cancellous bone. Finally are decribed histomorphometric parameters and their measurement using software I$mageJ2$ and plugin $BoneJ2$. In practical part of this thesis, there are described measurement procedure, measurement results, 3D geometry modelling procedure by reconstruction micro-CT images and determination of mechanical properties solved by computational modeling using FEM. Five speciments are analyse predominantly from os occipitale. On first specimen is analyzed influence of thresholding settings.
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