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Surfactant organogels as delivery systems for medical and cosmetic oils
Koláčková, Petra ; Mravec, Filip (referee) ; Pekař, Miloslav (advisor)
The aim of this thesis was to investigate the possible using of surfactant organogels in the cosmetic industry. Mainly, we focused on the ability of sugar surfactants to bind with medical (cosmetic) oil. With further heating, we observed transformation to the organogels. During the preparation of sugar surfactants, we decided to use the transesterification method. Another target was to verify functionality of this method and then proposed modifications to this process. Using Nuclear Magnetic Resonance, we checked the chemical structure of our sugar-based surfactants.
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Elastin hydrogels
Burianová, Veronika ; Trudičová, Monika (referee) ; Jugl, Adam (advisor)
This bachelor thesis is focused on elastin hydrogels for medical application. The aim of the experimental part was using elastin as an additional substance in polysaccharide gel matrices. The most available elastin material was elastin from bovine neck ligament. Because of the insolubility of elastin, it needed to be hydrolysed. Elastin was hydrolysed using potassium hydroxide. The hydrolysis product was soluble and thermal stable elastin peptides, called elastin. Prepared -elastin was incorporated in agarose gel matrices to produce semi-IPN hydrogels based on elastin and agarose. These hydrogels were characterized by rheologicalamplitude and frequency sweeps. The results of measuring clearly proved that -elastin addition caused increased hydrogel stiffness, but other changes were not observed.
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Surfactant organogels as delivery systems for medical and cosmetic oils
Koláčková, Petra ; Mravec, Filip (referee) ; Pekař, Miloslav (advisor)
The aim of this thesis was to investigate the possible using of surfactant organogels in the cosmetic industry. Mainly, we focused on the ability of sugar surfactants to bind with medical (cosmetic) oil. With further heating, we observed transformation to the organogels. During the preparation of sugar surfactants, we decided to use the transesterification method. Another target was to verify functionality of this method and then proposed modifications to this process. Using Nuclear Magnetic Resonance, we checked the chemical structure of our sugar-based surfactants.
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