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Conductive model of human tissue for electroporation purposes
Zelinková, Kateřina - Šarlota ; Cipín, Radoslav (referee) ; Novotná, Veronika (advisor)
This thesis solves the issue of the distribution of the high voltage pulse at the electroporation of the arget ablation zone. For futher examination of influence electroporation was necessary to first understand theoretically electrical charakter of cells and replace with basics eletrical circumferential elements (RLC). Based on this knowledge, theoretical prerequisites for experimental measurements were derived. Theoretical assumptions were then verified by experimental measurements. In the measurement, the assumptions found were confirmed, but significant performance losses were identified. A new catheter was designed to reduce the loss. Because the production of a new catheter is not economically disadvantageous, the properties of the new catheter were first tested using the simulation cloud environment SIMSCALE, where the heating of the heart tissue after the application of the electroporation pulse was monitored. Furthermore, the electroporation process was simulated in the FEMM program, where emphasis was placed on the propagation of cardiac tissue tension.
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Conductive model of human tissue for electroporation purposes
Zelinková, Kateřina - Šarlota ; Cipín, Radoslav (referee) ; Novotná, Veronika (advisor)
This thesis solves the issue of the distribution of the high voltage pulse at the electroporation of the arget ablation zone. For futher examination of influence electroporation was necessary to first understand theoretically electrical charakter of cells and replace with basics eletrical circumferential elements (RLC). Based on this knowledge, theoretical prerequisites for experimental measurements were derived. Theoretical assumptions were then verified by experimental measurements. In the measurement, the assumptions found were confirmed, but significant performance losses were identified. A new catheter was designed to reduce the loss. Because the production of a new catheter is not economically disadvantageous, the properties of the new catheter were first tested using the simulation cloud environment SIMSCALE, where the heating of the heart tissue after the application of the electroporation pulse was monitored. Furthermore, the electroporation process was simulated in the FEMM program, where emphasis was placed on the propagation of cardiac tissue tension.
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Selected technology monitoring in intesive care in a historical context
KNAJZLOVÁ, Petra
The diploma thesis presents the development of selected monitoring techniques of basic life functions in historical continuity. From the measured variables, this work includes measurements of cardiac activity, blood pressure, pulse, respiration and body temperature of the adults patients with intensice care in a historical context. This is a theoretical diploma thesis, which is divided into several chapters describing the history of nursing, a view of the monitoring in intesive care in the historical context to the presents. The first part of this historical work describes the beginnings of nursing. Its own origin and development, until now. The prestige of the nurse´s profession is formed by the society. In the leading positions in medicine previously dominated the men, in nursing care mainly women. A balanced relationship between a nurse and a doctor has been and is very important. The next part is devoted to the development of intensive care and the development of the role of the nurse in these departmenst. The history of intensive care has led to new partnership relationships between physician and nurse. There was an unfamiliar environment in which critical patients had to be cared for. This new role for the sister led to the increase of copetencies, there was a need to increase the education activity that focused on intensive care area. The view of urgent condition has changed over time. Already in the early sources, the urgent condition was described as a condition in which the health and life of the affected person is urgently threatened. These urgent conditions gave rise to the first beds for intensive care. Futher, the development of all monitoring techniques to date, servise of the monitoring technology. The negatives associated with monitoring technology are described too. The thesis will be used as a preview of changing nursing care in the context of changes in monitoring techniques of the intensive care.
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