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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Simulation of pharmacokinetic models
 Hejč, Jakub ; Jiřík, Radovan (referee) ; Mézl, Martin (advisor)
The theoretical part of this project is occupied with analysis of pharmacokinetic actions and also basic attributes of mathematical models used in pharmacokinetics. This description is mainly focused on models used for perfusion imaging methods. The aim of this project is to create an algorithm that simulates chosen models based on assigned parameters and also an algorithm that serves to fit experimentally measured data with a chosen model with a calculation of basic pharmacokinetic parameters. The next step of this solution is graphic interface realization which enables a full use of created algorithm in more accessible surroundings for the user. The result of this work is a program that can be used to obtain real data parameters and as well as a visual sample of the influence of these parameters on a process in a chosen functions.
Detailed record
Simulation of pharmacokinetic models
 Hejč, Jakub ; Jiřík, Radovan (referee) ; Mézl, Martin (advisor)
The theoretical part of this project is occupied with analysis of pharmacokinetic actions and also basic attributes of mathematical models used in pharmacokinetics. This description is mainly focused on models used for perfusion imaging methods. The aim of this project is to create an algorithm that simulates chosen models based on assigned parameters and also an algorithm that serves to fit experimentally measured data with a chosen model with a calculation of basic pharmacokinetic parameters. The next step of this solution is graphic interface realization which enables a full use of created algorithm in more accessible surroundings for the user. The result of this work is a program that can be used to obtain real data parameters and as well as a visual sample of the influence of these parameters on a process in a chosen functions.
Detailed record

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