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Cellular senescence and ageing-associated diseases
Antoš, Šimon ; Hodný, Zdeněk (advisor) ; Horníková, Daniela (referee)
In the last years more evidence supports the role of cellular senescence in ageing-associated diseases. Cellular senescence plays a role in these diseases on multiple levels and often directly supports their pathogenesis. The goal of this bachelor thesis is to summarize latest knowledge regarding the mechanism and the efect cellular senescence has in ageing-associated diseases, namely cancer, atherosclerosis, osteoarthritis, neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and multiple sclerosis, obesity and diabetes mellitus type two.

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