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Hydrogel matrices and nerve regeneration
Šindel, Matej ; Mravec, Filip (referee) ; Pekař, Miloslav (advisor)
Bachelor‘s Thesis is dealing with hydrogel materials appropriate for regeneration of neural tissue or neural tissue engineering. Contains two main parts. First part summarize results of literature research, which points out the complexity of neural system and reveals different demands of individual parts inside neural system. Second part describe simple experiments, where ability of preparation hydrogels using template with linear channels was checked. These linear channels could be filled with another hydrogel, but with different properties. Furthermore, the diffusion of model dyes in prepared linear channels was observed.
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Hydrogels and nerve tissue engineering
Šindel, Matej ; Mravec, Filip (referee) ; Pekař, Miloslav (advisor)
Master’s thesis deals with hydrogels suitable for neural tissue engineering. The thesis consists of a literature research with focus on understanding the parts of the neural system, the principles of used techniques and the requirements of the neural system for materials with potential to be used in neural tissue engineering. Then the thesis continues to the experimental part, where a simple model, created from agarose with linear channel filled with collagen mass, was designed. The individual materials used in model are prepared by various methods and then are tested. Testing includes verifying their ability or inability to fulfill the required functions. Ended by evaluating their potential of further use in more complex prototypes.
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Hydrogel matrices and nerve regeneration
Šindel, Matej ; Mravec, Filip (referee) ; Pekař, Miloslav (advisor)
Bachelor‘s Thesis is dealing with hydrogel materials appropriate for regeneration of neural tissue or neural tissue engineering. Contains two main parts. First part summarize results of literature research, which points out the complexity of neural system and reveals different demands of individual parts inside neural system. Second part describe simple experiments, where ability of preparation hydrogels using template with linear channels was checked. These linear channels could be filled with another hydrogel, but with different properties. Furthermore, the diffusion of model dyes in prepared linear channels was observed.
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