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Processing and analysis of the human lung microbiome from nanopore sequencing data
Molíková, Anna ; Bartoň, Vojtěch (referee) ; Nykrýnová, Markéta (advisor)
This bachelor’s thesis deals with processing and analysis of the human lung microbiome from nanopore sequencing data. Firstly this thesis introduces the lung microbiome and its composition in health and illness. Then it focuses on generations of sequencing technologies, mainly describing nanopore sequencing. The last chapter discusses different methods used for lung microbiome analysis. The practical part of this thesis preprocesses sequencing data, followed by their taxonomic analysis and the search for antibiotic resistance genes. From the obtained results, the composition of the lung microbiome in each of the processed samples is then evaluated.

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