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Assessment of impact of arrangement of collagen fibres in arterial wall on its response in tension tests
Kratochvíl, Filip ; Chamrad, Jakub (referee) ; Burša, Jiří (advisor)
This thesis deals with organisation of collagen fibres in human blood vessel walls and with simulation models, which are used to calculate vessel behaviour. Firstly, the thesis focuses on the anatomy of human blood vessel system, mainly on the vessel structure and properties of some vessel components. Next, two models are presented, which can be used for the vessel wall in calculations, specifically models with straight and wavy collagen fibres. Moreover, some methods are described, which can be used to gain information about a vessel. Subsequently, relationships are derived needed for simulation of tension tests of these models, mainly to express the length of collagen fibres. In the practical part simulations of vessel behaviour during uniaxial tension test are carried out and histograms of local direction angles of collagen fibres in the unloaded state are created. In the end, results gained by simulations are compared with real available data.
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Design of cylindrical apparatus for determination of directions of reinforcing fibres in aorta in its deformed state
Král, Martin ; Vaverka, Jiří (referee) ; Burša, Jiří (advisor)
This bachelor thesis deals with the design of cylindrical apparatus, which allows the cont- rolled biaxial deformation of a cylindrical sample of the aorta. This apparatus is designed to determine the direction of collagen fibers in the deformed aorta. The theoretical part of the thesis is focused mainly on description of the structure and mechanical properties of the wall of the aorta. In the design part, attention is paid to the design of the cylindrical apparatus. In the conclusion, the deformation of the cylindrical sample of the abdominal aorta from the pig is carried out on the apparatus and its strain is measured.
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Design of apparatus for determination of directions of reinforcing fibres in soft biological tissues in their deformed state
Sodomka, Tomáš ; Vaverka, Jiří (referee) ; Burša, Jiří (advisor)
The Bachelor´s thesis is focused on the determination of directions of collagen fibres in elastic arteries. The first aim of this thesis is a general introduction into soft tissue mechanics with turning attention to connective tissue where collagen fibres are their inseparable part. Also the thesis introduces arrangement of collagen fibres, their waviness and how the waviness thwarts determination of direction of fibres. The second aim is a design and test of the mechanical apparatus, which is able to stretch a squared aortic sample in two perpendicular directions (independently on each other) up to the relative deformation of 30 %. Design of the apparatus allows the sample to be dipped into the formaldehyde solution, which fixes the deformation. Consequent histologic sections of the sample will be used for the determination of global directions of collagen fibres in the aorta. The apparatus is designed to simulate conditions in a human or animal body where aorta is axially pre-stretched and at the same time expanded in the radial direction by blood pressure.
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Analysis of impact of direction distribution of collagen fibres in arterial wall on its mechanical properties
Fischer, Jiří ; Návrat, Tomáš (referee) ; Burša, Jiří (advisor)
The aim of this thesis is to analyse literature with focusing on literature about directional distribution of collagen fibres. This knowledge is very important for computational modelling and FEM analysis of arterial wall. Comparison of suitability of different models of directional distribution of collagen fibres is made by fitting of different types of probability density functions. Impact assessment of different collagen fibres distribution on mechanical properties of the arterial wall and impact assessment of wall anisotropy is solved with finite element method. FEM analysis is done on three loading types – uniaxial tension, equibiaxial tension and inflation of artery by internal pressure. Output of this thesis is evaluation of results for various types of collagen fibres arrangement in arterial wall.
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Analysis of impact of direction distribution of collagen fibres in arterial wall on its mechanical properties
Fischer, Jiří ; Návrat, Tomáš (referee) ; Burša, Jiří (advisor)
The aim of this thesis is to analyse literature with focusing on literature about directional distribution of collagen fibres. This knowledge is very important for computational modelling and FEM analysis of arterial wall. Comparison of suitability of different models of directional distribution of collagen fibres is made by fitting of different types of probability density functions. Impact assessment of different collagen fibres distribution on mechanical properties of the arterial wall and impact assessment of wall anisotropy is solved with finite element method. FEM analysis is done on three loading types – uniaxial tension, equibiaxial tension and inflation of artery by internal pressure. Output of this thesis is evaluation of results for various types of collagen fibres arrangement in arterial wall.
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|
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Assessment of impact of arrangement of collagen fibres in arterial wall on its response in tension tests
Kratochvíl, Filip ; Chamrad, Jakub (referee) ; Burša, Jiří (advisor)
This thesis deals with organisation of collagen fibres in human blood vessel walls and with simulation models, which are used to calculate vessel behaviour. Firstly, the thesis focuses on the anatomy of human blood vessel system, mainly on the vessel structure and properties of some vessel components. Next, two models are presented, which can be used for the vessel wall in calculations, specifically models with straight and wavy collagen fibres. Moreover, some methods are described, which can be used to gain information about a vessel. Subsequently, relationships are derived needed for simulation of tension tests of these models, mainly to express the length of collagen fibres. In the practical part simulations of vessel behaviour during uniaxial tension test are carried out and histograms of local direction angles of collagen fibres in the unloaded state are created. In the end, results gained by simulations are compared with real available data.
|
|
|
Design of cylindrical apparatus for determination of directions of reinforcing fibres in aorta in its deformed state
Král, Martin ; Vaverka, Jiří (referee) ; Burša, Jiří (advisor)
This bachelor thesis deals with the design of cylindrical apparatus, which allows the cont- rolled biaxial deformation of a cylindrical sample of the aorta. This apparatus is designed to determine the direction of collagen fibers in the deformed aorta. The theoretical part of the thesis is focused mainly on description of the structure and mechanical properties of the wall of the aorta. In the design part, attention is paid to the design of the cylindrical apparatus. In the conclusion, the deformation of the cylindrical sample of the abdominal aorta from the pig is carried out on the apparatus and its strain is measured.
|
|
|
Design of apparatus for determination of directions of reinforcing fibres in soft biological tissues in their deformed state
Sodomka, Tomáš ; Vaverka, Jiří (referee) ; Burša, Jiří (advisor)
The Bachelor´s thesis is focused on the determination of directions of collagen fibres in elastic arteries. The first aim of this thesis is a general introduction into soft tissue mechanics with turning attention to connective tissue where collagen fibres are their inseparable part. Also the thesis introduces arrangement of collagen fibres, their waviness and how the waviness thwarts determination of direction of fibres. The second aim is a design and test of the mechanical apparatus, which is able to stretch a squared aortic sample in two perpendicular directions (independently on each other) up to the relative deformation of 30 %. Design of the apparatus allows the sample to be dipped into the formaldehyde solution, which fixes the deformation. Consequent histologic sections of the sample will be used for the determination of global directions of collagen fibres in the aorta. The apparatus is designed to simulate conditions in a human or animal body where aorta is axially pre-stretched and at the same time expanded in the radial direction by blood pressure.
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