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Ecotoxicological evaluation of selected psychotropic drugs
Hricová, Nikoleta ; Řezáčová, Veronika (referee) ; Zlámalová Gargošová, Helena (advisor)
This bachelor thesis done by literary research is about the issue of the occurence of psychopharmacs in the enviroment. Psychopharmacs such as antidepressants, anxiolytics, hypnotics, sedatives etc. belong to one of the most sold drugs around the world. The consumption of psychopharmacs is concerning and growing. Therofore their occurence in nature is also growing, which can negatively affect the ecosystems. Many studies confirmed the persistency of psychopharmacs in nature, their following bioaccumulation and ecotoxicity for the representatives of each ecosystem. This bachelor thesis describes possible ways of the drug’s intersection (penetration) in nature, the metabolism of psychopharmacs in the human body and the effectivity of their elimination in sewage tanks. This work also focuses on the occurence, stability, degradability and persistency of psychopharmacs in aquatic and in terrestrial enviroment. The consideration of risks in the occurence of psychopharmacs for the representatives of each ecosystems was processed by many ecotoxicological studies, which point out the danger of these substances. Based on this acquired knowledge, in the conclusion of this work, there was drafted a battery of ecotoxicological tests for the estimated effects of psychopharmacs.
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Ecotoxicological evaluation of selected psychotropic drugs
Hricová, Nikoleta ; Řezáčová, Veronika (referee) ; Zlámalová Gargošová, Helena (advisor)
This bachelor thesis done by literary research is about the issue of the occurence of psychopharmacs in the enviroment. Psychopharmacs such as antidepressants, anxiolytics, hypnotics, sedatives etc. belong to one of the most sold drugs around the world. The consumption of psychopharmacs is concerning and growing. Therofore their occurence in nature is also growing, which can negatively affect the ecosystems. Many studies confirmed the persistency of psychopharmacs in nature, their following bioaccumulation and ecotoxicity for the representatives of each ecosystem. This bachelor thesis describes possible ways of the drug’s intersection (penetration) in nature, the metabolism of psychopharmacs in the human body and the effectivity of their elimination in sewage tanks. This work also focuses on the occurence, stability, degradability and persistency of psychopharmacs in aquatic and in terrestrial enviroment. The consideration of risks in the occurence of psychopharmacs for the representatives of each ecosystems was processed by many ecotoxicological studies, which point out the danger of these substances. Based on this acquired knowledge, in the conclusion of this work, there was drafted a battery of ecotoxicological tests for the estimated effects of psychopharmacs.
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