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National Repository of Grey Literature 3 records found  Search took 0.00 seconds. 
Theranostic systems in sonography
 Říkovská, Klára ; Pekař, Miloslav (referee) ; Mravec, Filip (advisor)
This work deals with preparation of microbubble suspension from a mixture of phospholipids, palmitic acid and polyethylene glycol. Properties of prepared systems were studied using bubble tensiometry and dynamic light scattering method and were compared with commercial contrast agent SonoVue®. Suspensions were prepared in various conditions including different atmosphere and increased temperature in some steps of preparation and different solution. Effect of polyethylene glycol addition on surface activity of the system was studied. Surface activity of phospholipids was insignificant. Surface tension decreased with increasing concentration and molecular weight of polyethylene glycol in the system. Effect of different atmosphere and increased temperature showed no substantial trend. It emerged that dynamic light scattering is not suitable for this type of samples because of high polydispersity and phase separation of the system.
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Modular Synthesis of Dendritic Amphiphiles.
 Edr, Antonín
The synthesis of such structures starts by an attachment of alkyl chain/s R and dendritic wedge/s to the starting molecules. These dendritic wedges are ended by three allyl groups so that various polar groups can be conjugated to the periphery of the wedge by so called thiol-ene click reaction. In addition to the resulting symmetrical structures, a synthesis of their unsymmetrical analogues bearing fluorescent tag on one of its arms (Figure 1) will be presented.
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Theranostic systems in sonography
 Říkovská, Klára ; Pekař, Miloslav (referee) ; Mravec, Filip (advisor)
This work deals with preparation of microbubble suspension from a mixture of phospholipids, palmitic acid and polyethylene glycol. Properties of prepared systems were studied using bubble tensiometry and dynamic light scattering method and were compared with commercial contrast agent SonoVue®. Suspensions were prepared in various conditions including different atmosphere and increased temperature in some steps of preparation and different solution. Effect of polyethylene glycol addition on surface activity of the system was studied. Surface activity of phospholipids was insignificant. Surface tension decreased with increasing concentration and molecular weight of polyethylene glycol in the system. Effect of different atmosphere and increased temperature showed no substantial trend. It emerged that dynamic light scattering is not suitable for this type of samples because of high polydispersity and phase separation of the system.
Detailed record

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