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Measurement of the respiratory sounds
Gottvald, Martin ; Rychtárik, Milan (referee) ; Kolář, Radim (advisor)
Respiratory sounds measurment This thesis deals with respiratory sounds analysis and measurment using digitalizing measuring cards and LabView environment. The anatomy of respiratory system is described, including each of its fractions and disturbances related to the respiratory system. The design of respiratory sounds amplifier is described, but wasn´t used considering the interferences of measured signal caused by the power-line frequency which results in substantial distortions. That's why, the previously recorded respiratory sounds were used for analysis in Matlab. The measuring program was designed in LabView, which alows signal recording from using acquisition card input and further processing.
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Experimental Research on Aerosol Transport and Deposition in a Human Respiratory Tract
Lízal, František ; Janotková, Eva (referee) ; Adamec, Vladimír (referee) ; Jícha, Miroslav (advisor)
Human health is significantly influenced by inhaled aerosols. Insight to the aerosol transport and deposition mechanisms is a prerequisite for both, toxicological protection against harmful particles and efficient application of inhaled therapeutic aerosols. The purpose of this doctoral thesis was to gain new knowledge of this topic on the basis of in vitro measurements. Phase-Doppler Anemometry was chosen for aerosol transport measurement, for it allows simultaneous measurement of particle size and velocity. Results were processed by means of statistical methods and frequency analysis. Deposition of spherical aerosol particles was measured by Positron Emission Tomography, while deposition of fibrous aerosol was measured by Phase-Contrast Microscopy combined with automated image analysis. All experiments were performed on physical models created on the basis of the real lung geometry. New knowledge of flow characteristics, transition from laminar to turbulent flow, effect of breathing pattern or particle size on aerosol transport and deposition in human lungs are outcomes of this work. Significant effect of the oral cavity was ascertained due to comparison of aerosol deposition in realistic and semi-realistic model with cylindrical smooth walls. Acquired data not merely extended our knowledge of aerosol behavior in lungs but it can also be used for validation of numerical simulations.
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Use of noninvasive pulmonary ventilation in pre-hospital emergency care
FILIPOVÁ, Lucie
Non-invasive pulmonary ventilation is a method that is commonly used in hospital care and is often the last way to avoid invasive airways in selected conditions. Despite the benefits it has for the indicated pacients, it is only exceptionally used in pre-hospital care and for some paramedics it is a method which they have little experience with. Likewise, their personal practice knowledge is often made up of only a few applications of non-invasive ventilation in a hospital. In my work I tried to create a comprehensive summary of information, which could help to unify non-medical healthcare personnel and at the same time to extend their knowledge in the issue, which is more discussed in the largest chapter of the theoretical part of this work. The aim of the work was to map the use of non-invasive pulmonary ventilation in pre-hospital urgent care in the South Bohemian Region and Vysočina Region and to find out about awareness of the health rescuers in selected regions. These objectives were implemented by a qualitative method through semi-structured interviews. The research showed that the use of the method in pre-hospital emergency care is not very widespread; that is is due to minimal experience and insufficient education of medical and paramedical staff. The awareness of paramedics about this issue is generally superficial. Most of their knowledge is made up only of personal experience that has been gained in use and is no longer expanded and coherent. This work could be further used as study material for non-medical healthcare staff.
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Experimental Research on Aerosol Transport and Deposition in a Human Respiratory Tract
Lízal, František ; Janotková, Eva (referee) ; Adamec, Vladimír (referee) ; Jícha, Miroslav (advisor)
Human health is significantly influenced by inhaled aerosols. Insight to the aerosol transport and deposition mechanisms is a prerequisite for both, toxicological protection against harmful particles and efficient application of inhaled therapeutic aerosols. The purpose of this doctoral thesis was to gain new knowledge of this topic on the basis of in vitro measurements. Phase-Doppler Anemometry was chosen for aerosol transport measurement, for it allows simultaneous measurement of particle size and velocity. Results were processed by means of statistical methods and frequency analysis. Deposition of spherical aerosol particles was measured by Positron Emission Tomography, while deposition of fibrous aerosol was measured by Phase-Contrast Microscopy combined with automated image analysis. All experiments were performed on physical models created on the basis of the real lung geometry. New knowledge of flow characteristics, transition from laminar to turbulent flow, effect of breathing pattern or particle size on aerosol transport and deposition in human lungs are outcomes of this work. Significant effect of the oral cavity was ascertained due to comparison of aerosol deposition in realistic and semi-realistic model with cylindrical smooth walls. Acquired data not merely extended our knowledge of aerosol behavior in lungs but it can also be used for validation of numerical simulations.
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Experimental research on aerosol transport and deposition in human respiratory tract
Lízal, František ; Jícha, Miroslav (advisor)
Human health is significantly influenced by inhaled aerosols. Insight to the aerosol transport and deposition mechanisms is a prerequisite for both, toxicological protection against harmful particles and efficient application of inhaled therapeutic aerosols. The purpose of this doctoral thesis was to gain new knowledge of this topic on the basis of in vitro measurements. Phase-Doppler Anemometry was chosen for aerosol transport measurement, for it allows simultaneous measurement of particle size and velocity. Results were processed by means of statistical methods and frequency analysis. Deposition of spherical aerosol particles was measured by Positron Emission Tomography, while deposition of fibrous aerosol was measured by Phase-Contrast Microscopy combined with automated image analysis. All experiments were performed on physical models created on the basis of the real lung geometry. New knowledge of flow characteristics, transition from laminar to turbulent flow, effect of breathing pattern or particle size on aerosol transport and deposition in human lungs are outcomes of this work. Significant effect of the oral cavity was ascertained due to comparison of aerosol deposition in realistic and semi-realistic model with cylindrical smooth walls. Acquired data not merely extended our knowledge of aerosol behavior in lungs but it can also be used for validation of numerical simulations.
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Measurement of the respiratory sounds
Gottvald, Martin ; Rychtárik, Milan (referee) ; Kolář, Radim (advisor)
Respiratory sounds measurment This thesis deals with respiratory sounds analysis and measurment using digitalizing measuring cards and LabView environment. The anatomy of respiratory system is described, including each of its fractions and disturbances related to the respiratory system. The design of respiratory sounds amplifier is described, but wasn´t used considering the interferences of measured signal caused by the power-line frequency which results in substantial distortions. That's why, the previously recorded respiratory sounds were used for analysis in Matlab. The measuring program was designed in LabView, which alows signal recording from using acquisition card input and further processing.
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