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Preventive effects of folic acid in nutrition
Chalánková, Veronika ; Bušová, Milena (advisor) ; Tláskal, Petr (referee)
This thesis is focused on folic acid and its preventive effects on human health. Folic acid has many important functions in the human body and is especially important during pregnancy. It is essential for the proper development of the fetus and its adequate intake is the prevention of serious congenital malformations, such as neural tube defects, premature birth, abortion and other pathologies. The increased need for this vitamin is not easy to supplement with a regular diet. It is therefore recommended to take it in the form of food supplements (400-600 µg/day) during pregnancy and at least one month before the planned conception. For these reasons, it is necessary to focus on supporting the primary prevention of folic acid use, preferably in all fertile women. Folic acid also plays a crucial role in hematopoiesis and the main manifestation of its deficiency is megaloblastic anemia. Folic acid is further associated with the prevention of cardiovascular and cancer diseases and influencing the development of cognitive functions. The practical part of this thesis was focused on monitoring the saturation of pregnant women with this vitamin. The work contains a laboratory analysis of the content of the metabolite folic acid 5-methyltetrahydrofolate (5-MTHF) in the urine of pregnant women in order to...
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The importance and need of folic acid during pregnancy
Mádle, Zuzana ; Starnovská, Tamara (advisor) ; Karbanová, Miroslava (referee)
Pregnancy places great strain upon the body of a woman. Many things contribute to a successful pregnancy, such as healthy eating habits, healthy lifestyle, adequate physical activity, fresh air, good mental health. It is recommended to begin folic acid supplementation even before conception. Folic acid, known as folate, is one of the B vitamins. Pregnancy places greater need for folic acid intake, especially in the early stages, where insufficiency or even deficiency can manifest in a pathological pregnancy, oftentimes fatal. The specific link between the two is not yet very well known. However, several studies have confirmed that there is a positive effect that comes with increased folic acid intake before conception and during the first few weeks of pregnancy, most notably reduced occurrence of neural tube birth defects. General population generally doesn't have adequate intake of folic acid, so there is usually a folic acid deficit before and during pregnancy as well. This can be countered by consuming food high in folate, targeted food enrichment or direct consumption of supplements containing folic acid. The Czech Republic currently doesn't enrich food with folic acid, therefore it is recommended to increase its intake via supplementation. Research investigation through paper questionnaires...
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Prenatal diagnosis by imaging methods
VLČEK, Martin
The bachelor degree thesis focuses on imaging methods in prenatal diagnostics. The theoretical part informs the readers about the current situation in this field, including invasive and noninvasive examination methods. The theoretical part is concluded with a chapter on prenatal detection of heart disease by means of screening examination of pregnant women. The objective of the thesis was to highlight the activities of a radiological assistant, to describe his/her activities during the use of various modalities and possibilities in diagnostics of congenital heart diseases, both prenatally and perinatally. One hypothesis was formulated, concerning the activity of a radiological assistant in diagnostics of congenital heart diseases during the prenatal period. The quantitative research was designed based on the number of examined fetuses and newborns in the teaching hospital (Fakultní nemocnice) in Motol and in the Center of Medical Genetics (Centrum lékařské genetiky s.r.o.) in České Budějovice in the course of 1 year. In 59 fetuses examined with magnetic resonance the following 3 congenital heart diseases were detected most frequently: 7 cases of agenesis of corpus callosum, 6 cases of ventriculomegalia and 7 cases of congenital cystic adenomatoid lung malformation. None of the examined mothers was diagnosed with placenta defects or pathological changes on the fetus heart. The formulated hypothesis has been confirmed. At present, congenital heart diseases are not routinely prenatally examined by means of magnetic resonance due to the too robust technology and insufficient quality of the imaging. The prominent role is still being played by ultrasonic examinations performed by gynecologists and obstetricians. The thesis and the research results may be used by cardiologists, gynecologists, obstetricians, as well as radiologists.
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The pregnancy problems by the women at the age after 35 years
LEDVINOVÁ, Lucie
Though medicine and nursing care have been advancing steadily, everybody is well aware that gravidity in older women poses certain risks, and after the 35th year of age it is not completely trouble-free. At the early stages of gravidity the fetus is endangered by a range of congenital defects of development. The expectant mother can experience problems not only during her pregnancy but also throughout the delivery itself. The pregnancy period may be accompanied by bleeding with the threat of possible miscarriage, premature delivery or some other serious complications looming. The paper aimed at finding whether women in the reproductive age were informed about the hazards of pregnancy after the age of 35; whether women used the method of in-vitro fertilization (IVF); what was the reason behind their decision to put off conception beyond the 35th year of age; and, finally, which nursing problems (nursing diagnoses) emerged attributable to the after-35 gravidity. The survey employed quantitative and qualitative methods. The quantitative investigation followed two objectives and examined two hypotheses. To obtain the required information, the survey relied on an anonymously completed questionnaire. The qualitative investigation pursued two objectives and research inquiries. The data were gathered through interviews and documentation processing. Both the objectives have been accomplished. Hypothesis 1: women within the age of fertility are familiar with the risks posed by the after-35 gravidity - confirmed. Hypothesis 2, not confirmed, expected women older than 35 years not to use the IVF method. With the research questions answered and the qualitative survey results evaluated, the author formulated these hypotheses: (1) Some women became pregrant after the age of 35 as they were unable to conceive earlier; (2) a difficulty that nurses have to tackle in the over-35 women is fatigue. The results of the paper could be beneficial for midwives or students in their future encounters with this subject, topical even today. The paper could also be found instructive by mothers contemplating gravidity after the age of 35.
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