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Bone implants based on Fe
Bachmayer, Marek ; Vondrák, Jiří (referee) ; Sedlaříková, Marie (advisor)
This thesis deals with usage of metal materials in bone implats creation process. This work also includes information about structure and attributes of bones, body fluids and content of iron in human organism. Following part of the paper deals with osteosynthesis, therefore commonly used methods of treating bone defects. Next part of this bachelor’s thesis is discussing the issue of biomaterials, biocompatibility and biodegradability of metal materials. Sample preparion procedure and description of samples, electrochemical corrosion and microscopic observation is included altogether with a pictorial documentation at the last chapters of this paper.
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Evaluation of the prediction of body composition measured by dual bioimpedance compared with bioimpedance spectroscopy.
Žídková, Natálie ; Hronek, Miloslav (advisor) ; Herink, Josef (referee)
KATEDRA BIOLOGICKÝCH A LÉKAŘSKÝCH VĚD Hodnocení predikce tělesné kompozice měřené bioimpedanční Natálie Žídková Vedoucí diplomové práce: doc. PharmDr. Miloslav Hronek, Ph.D. HRADEC KRÁLOVÉ, 2022/2023 ABSTRACT The aim of this work was to evaluate the prediction of body composition by the method of dual bioimpedance analysis in relation to the prediction of body composition by the method of spectroscopic bioimpedance analysis. Five pregnant women (first-time mothers) with a physiologically ongoing pregnancy were included in the study. Each of them participated in three examinations, specifically in the period between 17.-27. week of pregnancy, 28.-35. week of pregnancy and the 36th-38th week of pregnancy. A Tanita RD-953 personal digital scale (Tanita Corporation, Tokyo, Japan) representing dual bioimpedance analysis and a BCM - Body Composition Monitor (Fresenius Medical Care, Bad Homburg, Germany) representing spectroscopic bioimpedance analysis were used for measurements. The measurement results were compared by statistical analysis. No significant differences were found between the BIA and BIS measurements by the Wilcoxon test. In contrast, the Bland-Altman test found statistically significant differences in the measurement of body fat in the first and second follow-up periods, as well as in the...
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Proteomics of biological fluids
Jarkovská, Karla ; Kovářová, Hana (advisor) ; Petrák, Jiří (referee) ; Ulčová-Gallová, Zdeňka (referee)
Reproductive diseases, mainly those resulting in the infertility affect the chances of human being to reproduce. On the contrary, the heart disease, cancer and degenerative diseases currently account for majority of deaths in the world. Usually, these lifestyle diseases need longer lifespan to become the cause of death. The proteins secreted by cells carry important information about the cell's well-being, as well as about the condition of the tissues formed by these cells. Once secreted, these proteins may also be transferred throughout the body by means of body fluids, many of which are easily accessible for further 'in-depth' studies. Cellular and secreted proteins are often a focus of studies using proteomic means and the revelation of protein alterations can lead us to new ideas about the molecular mechanisms of diseases as well as possible identification of proteins that may be used as new targets for pharmaceutical intervention or molecules that could be used for diagnostic or prognostic purposes. Taking into consideration the above aspects, this research was undertaken to find proteins that could: (a) characterise the human follicular fluid as microenvironment of the maturing oocyte, to increase understanding of reproductive processes to improve the techniques of assisted repro- duction;...
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Bone implants based on Fe
Bachmayer, Marek ; Vondrák, Jiří (referee) ; Sedlaříková, Marie (advisor)
This thesis deals with usage of metal materials in bone implats creation process. This work also includes information about structure and attributes of bones, body fluids and content of iron in human organism. Following part of the paper deals with osteosynthesis, therefore commonly used methods of treating bone defects. Next part of this bachelor’s thesis is discussing the issue of biomaterials, biocompatibility and biodegradability of metal materials. Sample preparion procedure and description of samples, electrochemical corrosion and microscopic observation is included altogether with a pictorial documentation at the last chapters of this paper.
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