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The effect of electromagnetic fields on cell structure
Urbánek, Jiří ; Fiala, Pavel (referee) ; Vlachová Hutová, Eliška (advisor)
The main concern of the work is researching the influence of electromagnetic field on cellular structures. Cellular structures is a general term for all the organelles placed in a cell. In our 2D model we take into consideration just the fundamental organelles such as cell membrane, cytoplasm and cell nucleus. The aim of the work was to get acquainted with the outer environment into which we had placed the 2D model of the cell and on which we had applied the magnetic field. The work contains the results gained by numeric modelling in the physical programme COMSOL. These results prove the theoretical presumption.
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The effect of electromagnetic fields on cell structure
Urbánek, Jiří ; Fiala, Pavel (referee) ; Vlachová Hutová, Eliška (advisor)
The main concern of the work is researching the influence of electromagnetic field on cellular structures. Cellular structures is a general term for all the organelles placed in a cell. In our 2D model we take into consideration just the fundamental organelles such as cell membrane, cytoplasm and cell nucleus. The aim of the work was to get acquainted with the outer environment into which we had placed the 2D model of the cell and on which we had applied the magnetic field. The work contains the results gained by numeric modelling in the physical programme COMSOL. These results prove the theoretical presumption.
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Calculation of the Electromagnetic Field Around Microtubule
Havelka, D. ; Cifra, Michal
Microtubules are important structures in cytoskeleton which organizes the cell. Single microtubule is composed of electrically polar structures, tubulin heterodimers, which have strong electric dipole moment. Vibrations are expected to be generated in microtubules, thus tubulin heterodimers as electric dipoles are oscillating. This gives rise to electromagnetic field, which is detected around the cells. We calculate here the electromagnetic field of microtubules if they are excited at 1 GHz. This paper includes the work done in bachelor thesis of the first author.
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Measurement and Computer Simulation of Electromagnetic Oscillations of Living Cells
Cifra, Michal ; Pokorný, Jiří ; Vrba, J.
Frohlich postulated coherent polar oscillations as a fundamental biophysical property of biological systems. Recently, Pelling et al. (2004, 2005) detected mechanical vibrations of yeast cell membrane with atomic force microscope (AFM) and analyzed by Fourier analysis in the frequency range 0.5-2 kHz with amplitudes of the order of 1 nm. This article describes the measurement of electric activity of yeast cells in the acoustic frequency range and of mechanical vibrations of cell membrane. Spectrum analyzer and electrically and > electromagnetically screened box with point sensor and amplifiers fed by batteries were used for measurement of synchronized and non synchronized tubulin mutants of yeast cells. We show that the electric activity of synchronized cells in the M phase is greater that of non synchronized cells. That corresponds to the findings of Pohl et al. (1981). Obtained results of measurement of cell electric activity are in good agreement with AFM findings.
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Ultra low frequency yeast cells electric activity
Cifra, Michal ; Pokorný, Jiří ; Jelínek, František ; Hašek, Jiří ; Šimša, Jan
This paper presents results from the measurement of the electrical activity cold sensitive beta-tubulin mutant tub2-401 of yeast cells in frequency region 0.4 - 1.6 kHz. 25 measurements of both synchronized and nonsynchronized cells show that the synchronized cells have higher electrical activity what corresponds to the findings of Pohl et al. Mechanical oscillations of electrically polar structures in cell may give rise to electric oscillations we measured.
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Endogení elektrické pole a organizace živé hmoty
Pokorný, Jiří ; Hašek, Jiří ; Jelínek, František
Endogenous electromagnetic field with strong electric component generated by polar structures, in particular by microtubular structures, has important function in charge and mass transport which conditions biological activity. The Wiener-Lévy process is used for analysis of the transport with deterministic and random (thermal) components whose ratio may be important for biological function. Electric field can have dominant effect on directed transport at short and medium distances up to about 0.1 µm.
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Fröhlichův systém s modulovaným přístupem ke zdroji energie
Šrobár, Fedor
Fröhlich model describes coherent vibration modes of polar intracellular entities (e.g. protein molecules or microtubules) that are pumped by ATP hydrolysis and exchange energy with the surroundings. Kinetic equations expressing time change of the quantum oscillator occupancy contain the pumping rate, and the rates of change due to linear and nonlinear interactions with the phonons of the reservoir. These are analyzed supposing that the modal pumping rate is a decreasing function of the mode occupancy.
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